Multiple Sequence Alignment:
abLIM Download MSA
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abLIM human MPAFLGLKCLGKLCSSEKSKVtSSERTsARGSNRKRLIVEDRRVSGTS-FTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIkCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSssPKETTFSSNCAGCGRDIkNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEkDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEkLRP--------------------------------------------TRtssEsIysRPGssIPGsPGHtIyAKVDNEILDykDLAAIPKVkAIyDIERPDLItyEPFytsGyDDkQERQsLGEsPRtLsPtPsAEGyQDVRDRMIHRstsQGsINsPVysRHsytPtTSRSPQHFHRP----------------------------------------GNEPSSGRNSPLPYRPDSRPLtPTyAQAPKHFHVPDQGINIyRKPPIykQHAA--LAAQsKssEDIIkFSkFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRssGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERssLLAsRyDsPINsAsHIPSskTAsLPGyGRNGLHRPVstDFAQyNsyGDVSGGVRDyQtLPDGHMPAMRMDRGVsMPNMLEPKIFPyEMLMVtNrGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
abLIM iso2 human -----------------------------------------------------------MLMTLEMTEL--TDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP--------------------------------------------TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP----------------------------------------GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAA--LAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
abLIM iso5 human -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSssDFFys----------------KSLIRRTGRsPSLQPTRTssESIySRPGSSIPGSPGHTIyAKVDNEILDyKDLAAIPKVKAIyDIERPDLITyEPFyTSGyDDKQERQSLGESPRTLSPTPSAEGyQDVRDRMIHRSTSQGSINSPVySRHSYtPtTSRsPQHFH---------------------------------------------------------------------------RPDQGINIyRKPPIYKQHAA--LAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSsGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
abLIM mouse MPSLLGLKCLGKLCSSEIGKVPSPERASLRNSHRRLLI-EDLSVPETPDPAHRRRGTVIHLVYLYSAGCGPPELRFSSYDPSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSsPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGsPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPPNIPRSSsDFFYPKSLIRRTGRSPALQLLSPPCLTNSNKNPRQPTRtssEsIySRPGSSIPGsPGHTIyAKVDNEILDyKDLAAIPKVKAIyDIERPDLITYEPFYTSGYEDKQERQsLGEsPRtLsPtPsAEGyQDVRDRMIHRstsQGsINsPVySRHSYTPTTSRSPQHFHrPELLSPGVHRWSPLRTSSFSSTHSDSRPNPPFrHHFLPHVKGNEPSSGRNsPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIyRKPPIYKQHA--ALAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRssGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERAS-LASRyDsPLHSAsHAPSsKTSsLPGYGKNGLHRPVStDFAQYNsyGDISGGVRDYQTLPDGHMPAVRMDRGVsMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKkkAkLF
abLIM iso2 mouse -----------------------------------------------------------------------------MVKEKVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP--------------------------------------------TRtsSESIySRPGSSIPGsPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRsPQHFHRP----------------------------------------GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHA--ALAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERAS-LASRYDSPLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
abLIM iso3 mouse -----------------------------------------------------------------------------MVKEKVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP--------------------------------------------TRtsSESIySRPGSSIPGsPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRsPQHFH---------------------------------------------------------------------------RPDQGINIYRKPPIYKQHDAAALAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERAS-LASRYDSPLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRR----------
abLIM rat -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP--------------------------------------------TRTsSESIySRPGSSIPGsPGHTIyAKVDNEILDYKDLAAIPKVKAIyDIERPDLITyEPFyTSGYEDKQDRQsLGEsPRtLsPTPsAEGFQDGRDRMIHRStsQGsINsPVYSRHSYTPTTSRSPQHFH---------------------------------------------------------------------------RPDQGINIYRKPPIYKQHAA--LAAQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRRssGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKENRERASLLASRYDsPLHSASHAPSSKTSsLPGYGKSGLHRPVstDFAQyNSyGDVSGGVRDYQTLPDGHMPAMRMDRGVsMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
                                                             .. ..             .....:::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::...:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::*******************************:                                            ******************************************************************:***:*******************:**:************************************..                                        .................................:*****************:: .****:*:******************:*:*************:*::*:*::*********:*********************************:***:*.********::****:*****:******::******************:*****************:**********************************:***************:***********:******::::::::::
Consensus -----------------------------------------------------------------------------MVDEKVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP--------------------------------------------TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP----------------------------------------GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAA--LAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERASLLASRYDSPLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.