Multiple Sequence Alignment:
PAG	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 )
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PAG human	MGPAGSLLGSGQM--QITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHsGDHENLMNVPsDkEMFsRsVTsLATDAPAsSEQNGALTNGDILSEDs tLTCMQHyEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARsVDGDQGLGMEGPyEVLKDSs sQENMVEDCLyEtVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEyAsVDRNKKCRQsVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTsETNKRFs sLs yKsREEDPtLTEEEIsAMy s sVNKPGQLVNKSGQSLTVPEs t y t sIQGDPQRsPs sCNDLyAtVKDFEKTPNS--TLPPAGRPsEEPEPDyEAIQtLNREEEKATLGtNGHHGLVPKENDyEsIsDLQQGRDITRL
PAG mouse	MGPAGSVLSSGQMQMQMVLWGSLAAVAMFFLITFLVLLCSTCDREKKPRQHSGDHENLMNVPSDKDMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLTCMQHyEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDEILTARAADTELGPGVEGPyEVLKDs s sQENMVEDCLyETVKEIKEVA-----DKGQGGKSKsTSALKELQGAPMEGKADFAEyASVDRNKKCRHsANAESILGTCsDLDEEsPPPVPVKLLDENANLPQEGGGQAEEQAAEGtGGHsKRFs sLsYKSREEDPTLTEEEISAMySSVNKPGQSAHKPGPCMKGPESACHsMKGLPQRSSs sCNDLyAtVKDFEKTPNSISTLPPARRPsEEPEPDyEAIQTLNREDEKVPLETNGHH--VPKEsDyEsIGDLQQCRDVTRL
PAG rat	MGPAGSALSSGQMQMQMVLWGSLAAVAMFFLITFLILLCSSCDRDKKPRQHsGDHEsLMNVPsDKEMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDAMLTARAADGDsGPGVEGPyEVLKDSSSQENMVEDCLyETVKEIKEVA-----DKSQGGKSKSTSALKELQGAHAEGKADFAEyASVDRNKKCRHSTNAESILGTSsDLDEETPPPVPVKLLDENANLPEKGEHGAEEQAPEAPSGHSKRFs sLSYKSREEDPTLTEEEISAMy sSVNKPGQsAHKPG-----PESTCQCPQGPPQRSSSsCNDLyATVKDFEKTPNSISMLPPARRPGEEPEPDyEAIQTLNREDDKVPLGTNGHL--VPKENDyESIGDLQQGRDVTRL
	*****::***::::*******::**::::*******:****:::*::****:********:*********************:**********:::**::::.::*******************************.....:::::*:::.:**:***********:::***::::::********:::::::.**:::::::::*********************************::::.....*::.:.:.**:***************:::::***************:::::*:..:*:::***
Consensus	MGPAGSALSSGQMQMQMVLWGSLAAVAMFFLITFLILLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDAMLTARAADGDQGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVA-----DKGQGGKSKSTSALKELQGAQAEGKADFAEYASVDRNKKCRHSANAESILGTSSDLDEEAPPPVPVKLLDENANLPEKGGGQAEEQAAEATSGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGQCLKGPESTCQSIQGDPQRSSSSCNDLYATVKDFEKTPNSISTLPPARRPSEEPEPDYEAIQTLNREDEKVPLGTNGHH--VPKENDYESIGDLQQGRDVTRL

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.