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BUB1B human	MAAVKKEGGALSEAMsLEGDEWELSkENVQPLRQGRIMstLQGALAQ-ESACNNtLQQQkRAFEyEIRFYTGNDPLDVWDRYIsWTEQNYPQGGKESNMSTLLERAVEALQGEkRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRkADAIFQEGIQQkAEPLERLQSQHRQFQARVSRQTLLALEkEEEEEVFESSVPQRSTLAELksKGKKtARAPIIRVGGALk K250-ac K250-ub K250-sm APSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAkENELQAGPWNtGRsLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCKIEPSINHILstRkPGKEEGDPLQRVQsHQQASEEKKEKMMYCKEKIyAGVGEFSFEEIRAEVFRKKLKEQREAELLtsAEkRAEMQKQIEEMEkKLkEIQTTQQERTGDQQEEtMPTkETTkLQIASESQkIPGMTLSSSVCQVNCCARETSLAENIWQEQPHsk-----GPSVPFSIFDEFLLsEkKNksPPAD-PPRVLAQRRPLAVLKTSESITSNEDVsPDVCDEFTGIEPLSEDAIITGFRNVtICPNPEDtCDFARAARFVStPFHEIMSLkDLPsDPERLLPEEDLDVKTSEDQQTACGTIySQTLsIkkLsPIIEDsREAtHSsGFSGSSASVASTSsIkCLQIPEkLELtNETSENPTQsPWCSQYRRQLLKsLPELSASAELCIEDRPMPKLEIEkEIELGNEDyCIkREYLICEDYKLFWVAPRNSAELtVIKVsSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLsPRCLILRNRIHDPYDC-NkNNQALKIVDFSYSVDLrVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELkDGELWNkFFVRILNANDEAtVSVLGELAAEMNGVFDTTFQSHLNKALWkVGkLtsPGALLFQ------------
BUB1B iso2 human	MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQ-ESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGE------------------------------------------------------NFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKVSLSLGPSVPFSIFDEFLLSEKKNKSPPAD-PPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPED--------------------------------------------------------------------SREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC-NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSHLNKALWKVGKLTSPGALLFQ------------
BUB1B mouse	-------MAEAsEAMCLEGAEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQKRAFESEIRFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDPRFLSLWIKLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGIERKAEPLDRLQSQHRQFQSRVSRQAFLALGNEE-EEALEPSEPQRSSLAELKsRGKKMARAPISRVGGALkAPGQSRGFLNAVPQPVHGNRRITVFDENADTASRTELSKPVAQPWMAPPVPRAKENELQPGPWSTDRPAGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCKIEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIyAGVGEFSFEEIRAEVFRKKLKERREAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKMPTEDPARLQIASGPQEMSGVPLSCSICPLSSNPREIsPAENILQEQPDS-----KGsSMPFSIFDESLSDK-KDKsPATGGPQVLNAQRRPLSVLKTTEVGTTNEDVSPDICDELTELEPLSEDAIITGFRNVTLCPNPEDTCDFARAARLASTPFHEILSSKGIAADPEGLLQEEDLDGKAAEAHH----TVHHQALIIKKLsPIIEEsREAtHSSGFSRSSsSAPsTSSIKGFQLLEKLELTNDGAEDAIQSPWCSQYRLQLLKSLLELSAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPRSSAELTMIKASSQPIPWDFYINLKLKERLNEDYDQLCSCCQYQDGHVVWYQYINCSTLQNLLQHSEFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLsPRSLILRNRIHDPYDYVNKDDHAVRIMDFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIADLAHLLLFKEHLHVFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAAEMGGAFDATFHSHLNRALWKLGKTIsPEALLTQQDKQPGGSQsPA
BUB1B rat	-------MAAASEATCVEGDEWELSKENVQPLRHGRIMATLQGALAQQESACSTTLQQQKWAFESEIRFYSGNDPLDVWDRYINWTEQNYPQGGKESNMSTLLERAIEALQGEKRYYSDPRFLNLWIKLGHLCNEPLDMYSYLHSQGIGISLAQFYISWAEEYEARENFKKADIVFQQGIECKAEPLDRLQSQHRQFQARVSRQALLALGNEE-EEVLGSSEPQRSTLAELKSRGKKMARAPINRVGGALKAPGQSRGFLNTLPQPVHSNRRITVFDENADSASRPELSKPVAQPWMAPPVPRAKENELQPGPWNTDRPLEYRPHSNPASVTSVPSVLPNFTPYVEESAQQTVMTPCKIEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKERREAELLTSAKKREEMQKQIEEMERKLKAMQTIQQERAGDQQEERMLSKDSARLEIASESQEMSGVPPSCSIWPLSSNPREISPAENILQEQPET-----KGPSMPFSIFDESLSDK-KDKSPATDGPQVLNAQRRPLTVLKTTEVIPANEDISPDVCDELTEIEPLSEDAIITGFRNGILCPNPEDTCDFARAARFASTPFHEILPSKSIASDPKEGLQEEDLDGKATEGHH----IVHLQTLSVKKLSPIIEDSREATHSSGFSRSSSSVTSTSSIKGFQILEKLELTTDAAENAIQSPWCSHYRLQLLKSLPELSAFAEFSVEDRPMPMLELGKEIELGHEDYCIKQEHLTCEDYRLFWVAPRNSAELTMIKASSQPLPWDFYINLKLKERLNEDCDQLCSCCQYQDGHVVWYQYINCSTLQDLLQHSEFVTHEIIVLIICNLLTIVEKLHKAEIVHGDLSPRSLILRNRIHDPYDYINKDDHAVRIVDFSYSVDMRVQLDAFAYSGFRTAQVLEGQKILANCSSPYQVDLLGIADLAHLLLFKEHLHVFWDGLLWRLSQNTSELKDGELWNKFFVQILNASDKSTVFILRELAAEMSGAFDTTFHSHLNKALWKLGKVISPEASLIQQDKQSSLLQNPA
	.......::::***:::**:********:****:**:*:*******:.***:.::*****:***:*****:*:**********:****************:*:***:******.:::.:::::.::.:::.::::::::::::..::::.:::::::::::::::::**:***::**:**:.*****:**********:*****::***::**.**::::*:****:******:***:*****.*********:*:**::*:.**:::.*:**********.**::*****::***:***:*********:***:*:*:::.**:.*:**::::*:***:*******:*:*:*************:*******:**************::*************************************:*********:**:**********::**::*:.***::*:****.*::::.::*:***::*:::*:::*:*::::::::**:*:****:****.:.    .*:*:*******:*:::.*:***:::.*::::******:****:*::::***:***:***:*::**************:::******:::::::::..:::::::...:...:::...:.:::::.:..:...    ....:::..::::::::.***********:**:*::******::*::******::::*:::******:**:******:****:**:::******.**::******.***:**:*:*:*:**:*******:*****:**:****:*****************.*::***:*****::**:*****:***:******::****:****:*******:**:***********:************:.**:::*::*:*******:*****:*::*****:*:**************:***:***************:*****::*:***::*****:********:****:*::**::*:******.*:**:**:****:****:**.:**:*:*.*............
Consensus	MAAVKKEGAAASEAMCLEGDEWELSKENVQPLRQGRIMSTLQGALAQQESACNNTLQQQKRAFESEIRFYSGNDPLDVWDRYINWTEQNYPQGGKESNMSTLLERAIEALQGEKRYYSDPRFLNLWIKLGHLCNEPLDMYSYLHSQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLDRLQSQHRQFQARVSRQALLALENEEEEEVLESSEPQRSTLAELKSRGKKMARAPIIRVGGALKAPGQNRGLQNPFPQQMQNNRRITVFDENADEASRAELSKPTAQPWIAPPMPRAKENELQAGPWNTDRPLEHRPRGNPASLIAVPAVLPSFTPYVEESARQPVMTPCKIEPSINHILSTRKPGREEGDPLQRVQSHQQACEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKERREAELLTSAEKRAEMQKQIEEMERKLKAIQTTQQERAGDQQEETMPTKDTARLQIASESQEIPGMPLSCSICQLNCNAREISLAENILQEQPHSK----KGPSMPFSIFDEFLLDEKKNKSPAADGPQRLNAQRRPLAVLKTSESITSNEDVSPDVCDELTEIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFASTPFHEILSSKDIASDPERLLQEEDLDGKAAEAHH----TVHHQTLSIKKLSPIIEDSREATHSSGFSRSSASVASTSSIKCLQILEKLELTNDTAENAIQSPWCSQYRRQLLKSLPELSAFAELCIEDRPMPKLEIEKEIELGNEDYCIKREHLICEDYRLFWVAPRNSAELTMIKASSQPVPWDFYINLKLKERLNEDFDQLCSCCQYQDGCIVWHQYINCFTLQDLLQHSEFITHEIIVLIIYNLLTIVEKLHKAEIVHGDLSPRCLILRNRIHDPYDC-NKNNQALRIVDFSYSVDLRVQLDAFALSGFRTAQILEGQKILANCSSPYQVDLLGIADLAHLLLFKEHLQVFWDGLLWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGAFDTTFQSHLNKALWKLGKLISPEALLFQQDKQ----Q-PA