Multiple Sequence Alignment:
AurB Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340         )
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AurB human MAQkENsyPWPyGRQtAPsGLSTLPQRVLRkEPVtPSALVLMSRsNVQPTAAPGQkVMENssGtP----DILT-RHFtIDDFEIGRPLGk
Gk
FGNVyLAREKkSHFIVALKVLFkSQIEkEGVEHQLRREIEIQAHLHHPNILRLYNYFYDrRRIYLILEYAPRGELYkELQkSCTFDEQRTATIMEELADALMYCHGkKVIHRDIk
PENLLLGLkGELk
IADFGWSVHAPsLRRktMCGtLDyLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVkVDLkFPASVPMGAQDLISkLLRHNPsERLPLAQVSAHPWVRANsRRVLPPSALQSVA
AurB iso2 human MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTP----DILT-RHFTIDDFEIGRPLGKALLCLW--------------------------------PEASSVSSPSHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
AurB iso5 human MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTP----DILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
AurB mouse MAQKENAYPWPYGSKTsQSGLNTLSQRVLRKEPATTSALALVNRFNSQSTAAPGQKLAENKSQGSTASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREkkSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKVIHRDIkPENLLLGLQGELKIADFGWSVHAPsLRRKtMCGtLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVRANSRRVLPPSAL----
AurB rat MAQKENVYPWPYGSKTSQSGLNTLPQRVLRKEPAVTPAQALMNRSNSQSTAVPGQKLTENK--GATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKtMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHNPSQRLPLEQVSAHPWVRANSRRVLPPSAL----
AurB pig MAQKENTYPWPYGRQTAQSGLNILPQRVLRKEAVTPSALVLMSRSNTQPTAAPGQKVVENSSGTP----NFST-RSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALIYCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKtMCGTLDYLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLISKLLKHNPSDRLPLAQVSAHPWVRAHSRRVLPPSAPQSVP
  ******:******::*::***::*:*******:::::*::*::*:*:*:**:****::**:::::.. .::::.::****:*********::::::::::::::.::::::.:::::::::::::::::*:::::::.*****:*******::********************::**************:***:***:*****************:*************************************:***:*************:********:**:******:*******:*:*:**:*******:***::****::*:*******:*********::::.
Consensus MAQKENSYPWPYGRQTAQSGLNTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTP----DILT-RHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.