(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580        )
	|         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |
Lamin B1 human	MAtAtPVP-PrMGsrAGGPttPLsPtRLsRLQEk K33-ac K33-ub EELRELNDrLAVyIDk K49-ac K49-ub VRSLETENsALQLQVTEREEVRGRELtGLk K79-ac K79-ub ALyEtELADARRALDDTARERAk K102-ac K102-ub K102-sm LQIELGkCk K111-ac K111-ub AEHDQLLLNYAk K123-ac K123-ub K123-sc kEsDLNGAQIk K134-ac K134-ub LREyEAALNskDAALATALGDk K156-ac K156-ub k K157-ac K157-ub sLEGDLEDLkDQIAQLEASLAAAk K181-ac K181-ub K181-sc kQLADETLLKVDLENrCQsLTEDLEFRk K209-ac K209-ub sMyEEEINETRRkHETRLVEVDsGRQIEyEYk K241-ub K241-sm LAQALHEMrEQHDAQVRLYk K261-ub K261-sm K261-sc EELEQtyHAk K271-ac K271-ub LENARLssEMNtstVNsAREELMESrMrIEsLssQLSNLQk K312-ac K312-ub ESRACLERIQELEDLLAkEKDNSRRMLtDkEREMAEIRDQMQQQLNDyEQLLDVKLALDMEIsAyRk K379-ac K379-ub K379-sm LLEGEEErLk K389-ac K389-ub K389-sm LsPsPssRVtVsRAsssRsVRttRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLkNTsEQDQPMGGWEMIRk K474-ac K474-ub IGDTsVsYk K483-ac K483-ub YTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVkVILk K532-ac K532-ub NsQGEEVAQRSTVFkTTIPEEEEE-EEEAAGVVVEEELFHQQGtPRASNRSCAIM
Lamin B1 mouse	MAtAtPVQQQRAGsrAsAPAtPLsPtRLsRLQEkEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLkALYEtELADARRALDDTARERAkLQIELGk K110-ac K110-ub Fk K112-ac K112-ub AEHDQLLLNYAKkESDLSGAQIkLREYEAALNSKDAALATALGDKksLEGDLEDLkDQIAQLEASLSAAkkQLADEtLLkVDLENRCQsLTEDLEFRkNMYEEEINETRRKHETRLVEVDsGRQIEYEYKLAQALHEMREQHDAQVRLYk K262-ac K262-ub EELEQTYHAk K272-ac K272-ub LENARLsSEMNtsTVNSAREELMESRMRIEsLSSQLsNLQkESRACLERIQELEDMLAk K331-ac K331-ub ERDNSRRMLSDREREMAEIRDQMQQQLsDYEQLLDVKLALDMEIsAYRk K380-ac K380-ub LLEGEEERLkLsPsPssRVtVsRAsssRsVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYkYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILkNSQGEEVAQRsTVFkTTIPEEEEEEEEEPIGVAVEEERFHQQGAPRASNKSCAIM
Lamin B1 rat	MATATPVQ-QRAGSRASAPATPFSPTRLSRLQEkEELRELNDRLAVYIDkVRSLETENSALQLQVTEREEVRGRELTGLkALYETELADARRALDDTARERAkLQIELGkFkAEHDQLLLNYAKKEsDLSGAQIkLREYEAALNSKDAALATALGDKksLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYkLAQALHEMREQHDAQVRLYkEELEQTYHAkLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAkERDNSRRMLSDkEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRkLLEGEEERLKLsPsPSSRVTVSRAsSsRsVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYkYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVkVVLKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLEEERFHQQGtPRASNKSCAIM
Lamin B1 cow	MATATPVP-PRSGSRAGGPAtPLsPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLESDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVKLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEE-EEEAAEVAVEEELFHQQGAPRGSNRSCAIM
	*******: :*:****::*:**:***************************************************************************************:******************:*******************************:****************:*******************************:***********************************************:********************************:::*******************:*************:****:*******:*:***************:*******************************************************************************************************************************************:*******************************:**************************.***:::*::***:*****:**:**:*****
Consensus	MATATPVQ-QRAGSRAGAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEEAAGVAVEEERFHQQGAPRASNRSCAIM