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SPEG human	MQKARGTRGEDAGTRAPPsPGVPPKRAKVGAGGGAPVA--VAGAPVFLRPLKNAAVCAGsDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRRLPGsPRQAQAtGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGsAFsLYRGRALsIHVSVPQSGLRREEPDLQPQLASEAP-RRPAQPPPSKSALLPPPsPRVGKRSPPGPPAQPAATPt sPHRRTQEPVLPEDTT-TEEKRGKKSKSSGPSLAGTAEsRPQtPLsEAsGRLSALGRsPRLVRAGsRILDKLQFFEERRRSLERSDsPPAPLRPWVPLRKARsLEQPKSERGAPWGtPGAsQEELRAP-GSVAERRRLFQQKAAsLDERTRQRsPAsDLELRFAQELGRIRRSt sREELVRsHESLRATLQRAPsPREPGEPPLFsRPsTPKTSRAVsPAAAQPPsPSsAEkPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLtRSRAIQECRsPVPPPAADPPEARtKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPsPsQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFtRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPsIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLsDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPETGAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGs sAESALPRAGPRELGRGLHKAAsVELPQRRsPsPGATRLArGGLGEGEYAQRLQALRQRLLRGGPEDGkVSGLRGPLLESLGGRARDPRMARAAsSEAAPHHQPPLENRGLQKs s sFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVAsPPPGAPEKRVPSAGGPPVLAEKARVPtVPPRPGSSLSSSIENLESEAVFEAKFKRSREsPLSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRsVQDLRAVGEPGLVRRLsLSLsQRLRRTPPAQRHPAWEARGGDGESSEGGSsARGsPVLAMRRRLsFTLERLSSRLQRsGSSEDSGGASGRsTPLFGRLRRAt sEGESLRRLGLPHNQLAAQAGAtTPsAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLsIPRAGKRHAGLYECsATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQtPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPEPTKVTVQSLsPAKEVVSSPGs sPRsSPRPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAAtRHKVLLRSYPGGP
SPEG iso1 human	MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAPVA--VAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAP-RRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTT-TEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAP-GSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPETGAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGPPVLAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSSCLSVCHKEIKMASS--------------------------------------------
SPEG mouse	MQKARGTRGEDAGTRAPPsPGVPPKRAKVGAGrGVLVTGDGAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLSWFRDGQLLPPPAPEPSCLWLRSCGAQDAGVYSCSAQNERGQASCEAVLTVLEVRDSETAEDDISDVPGTQRLELRDDRAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRPLPGSPRQAQTTGAGPRHLGVEPLVRAsRANLVGASWGSEDSLSVASDLYGSAFSLYRGrALSIHVSIPPSGLHREEPDLQPQPASDALRPRPALPPPSKSALLPPPsPRVGKRALPGPSTQPPAtPTSPHRRAQEPSLPEDITTTEEKRGKKPKsSGPSLAGTVEsRPQtPLsEAsGRLsALGRsPRLVRAGsRILDKLQFFEERRRSLERSDsPPAPLRPWVPLRKARsLEQPKsEGGAAWGtPEAsQEELRsPRGSVAERRRLFQQKAAsLDERTRQRsATsDLELRFAQELGRIRRSTsREELVRsHEsLRATLQRAPsPREPGEPPLFsRPs tPKTSRAVsPAATQPPPPSGAGKSGDEPGRPRsRGPVGRTEPGEGPQQEIKRRDQFPLTRSRAIQECRsPVPPYTADPPESRTKAPSGRKREPPAQAVRFLPWATPGVEDSVLPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGTRSQGKGRRARPt sPELEsSDDSYVsAGEEPLEAPVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSMLHSEGRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQATCASSLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKLsPsQDHDSSDSSSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPADVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARLDCKISGTPPPSVTWTHFGHPVNEGDNLRLRQDGGLHSLHIARVGsEDEGLYEVSATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPsIPEEPEHGDLERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDIHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPEVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPAWAATGLKKGIQHIFRVLSSSGKSSSKPSAPSEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEARTGVYELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSVTLELAEAPRFEsIMEDVEVGPGETARFAVVVEGKPLPDIMWYKDEVLLAESNHVSFVYEENECSLVLLsAGSQDGGVYTCTARNLAGEVSCKAELSVLSAQTAMEVEGVGEDEEHRGRRLsDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHGCVLYFHEAFERRRGLVIVTELCTEELLERMARKPTVCESETRTYMRQVLEGICYLHQSHVLHLDVKPENLLVWDGAGGEEQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTEAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRRQPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPEAGAATPMDWQEQERtPSKDQEAPsPEALPsPGQEsPDGPSPRRPELRrGs sAESALPRVGSREPGRSLHKAAsVELPQRRsPsPGATRLTr R2060-m1 R2060-m2 GGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLEsLGGRARDPRMARAAsSEAAPHHQPPPESRGLQKSs sFSQGEAEPrGRHRRAGAPLEIPVARLGARRLQESPsLSALsETQPPsPARPsVPKLSITKSPEPSAVTSRDSPQPPEPQPVPEKVPEPkPEPVRAAKPAQPPLALQMPTQPLTPYAQIMQSLQLSSPTLSP-QDPAVPPSEPKPHAAVFARVAsPPPGVSEKRVPSARtPPVLAEkARVPTVPPRPGSSLSGSIENLESEAVFEAKFKRSRESPLSRGLRLLSRsRsEERGPFRGAE-DDGIYRPsPAGtPLELVRRPERSRsVQDLRVAGEPGLVRRLsLsLsQKLRRtPPGQRHPAWESRSGDGESsEGGSsARAsPVLAVRRRLs s tLERLs sRLQRsGs sEDsGGAsGRs tPLFGRLRRATsEGEsLRRLGVPHNQLGSQTGATTPsAEsLGSEASGTSGSSAPGESRSRHRWGLSRLRKDKGLsQPNLSSSVQEDLGHQYVPSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPRISWMKDKQSLRSEPSVVIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARIPGKLAPPEVPQTYHDTALVVWKPGDGRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTQLPVGVTVRFRVACSNRAGQGPFSNPSEkVFIRGtPDsPAQPAAAPRDAPVTsGPTRAPPPDSPTSLAPTPALAPPASQASTLSPSTSSMSANQALSSLKAVGPPPAtPPRKHRGLLATQQAEPSPPSIVVTPSEPRSFVPDTGTLTPTSSPQGVKPAPSSTSLYMVTSFVSAPPAPQAPAPEPPPEPTKVTVRsLsPAkEVVSs--------PTPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGkRRVLQEYEVLRTLHHERLMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLAADNALKIVDFGSAQPYNPQALkPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP
SPEG rat	MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGRGVLVTGAGAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPEPSLSWFRDGQLLPTPVPEPSCLWLRNCGAQDAGVYSCSAQNERGKASCEAVLTVLEVRDSETAEDDIsDVPGTQRLELRDDRAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRPLPGSPRQAQTTGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSIPPSGLRREEPDLQPQPASDALRPRPALPPPSKSALLPPPSPRVGKRALPGSSAQPPATPTSPHRCTQEPSLPEDITTTEEKRGKKPKSSGPsLAGTVEsRPQtPLsEAsGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDsPPAPLRPWVPLRKARsLEQPKSEGGAAWDtPGAsQEELRsPRGSVAERRRLFQQKAAsLDERTRQRSATsDLELRFAQELGRIRRSTsREELVRsHESLRATLQRAPSPREPGEPPLFSRPSIPKTSRAVsPAATQPPPPSGAGKSGDETGRPRSRGPVGRTEPGEGPQQEIKRRDQFPLTRSRAIQECRSPVPPFTADPPESRTKAPSARKREPPAQAVRFLPWATPGVEDSVLPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGTRSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSVLHSEGRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQASCASSLAVRPGASTSPFSSPITSDEEYLSPPEEFPEPGETWSRTPTMKPSPSQDRDSSDSSSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPADVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTVKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARLDCKISGTPPPSVTWTHFGHPVNESENLRLRQDGGLHSLHIARVGSEDEGLYEVSATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPsIPEEPEHGDLERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDIHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPEWAATGLKKGLHHIFRVLSSSGKSSSKPSAPSEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEPRTGVYELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSITLELAEAPRFESIMEDVEVGPGETARFAVVVEGKPLPDIMWYKDEVLLAESNHVSFVYEENECSLVVLSAGSQDGGVYTCTARNLAGEVSCKAELSVHSAQTAMEVEGVGEDEEHRGRRLSDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERMARKPTVCESETRTYMRQVLEGIGYLHQSHVLHLDVKPENLLVWDGAGGEEQVRICDFGNAQELTPGEPQYCQFGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTEAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRRQPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPEAGAATPMDWQEQGRAPSKDQEAPsPEALPSPGQEsPDGPSPRRPELRRGs sAESALPRVGSREPGRSLHKAAsVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAAsSEAAPHHQPPPESRGLQKSSsFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSETQPPsPALPSAPKPSITKSPEPSAATSRDsPQPPAPQPVPEKIPEPKPEPVRAAKPAQPPLALQMPAQSLTPYAQIMQSLQLSSPTLSP-Q---VPPSEPKPHAAVFARVASPPPGASEKRVPSARIPPVLAEKVRVPTVPPRPGSSLSGSIENLESEAVFEAKFKRSRESPLSRGLRLLSRSRSEERGPFRGAE-DDGIYRPSPAGTPLELVRRPERsRSVQDLRVAGEPGLVRRLsLsLsQKLRRTPPGQRHPAWEsRSGDGEs sEGGSsARGsPVLAVRRRLs sTLERLSSRLQRSGsSEDSGGAsGRStPLFGRLRRAt sEGEsLRRLGVPHNQLASQTGATTPSAESLGSEASGTSGSSAPGESRSRHRWGLSRLRKDKGLsQPNLSASVQEDLGHQYVPSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPTPRISWMKDKQSLRSEPSVVIVSCKDGRQLLSIPRASKRHAGLYECSATNVLGSITSSCTVAVARTPGKLAPPEVPQTYCDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTQLPVGVTVRFRVACSNRAGQGPFSNPSEKVFIRGTQDsPAQSAAAPRDAPVTSGPTRAPPPDSPTSLVPTPPLAPQVSQASTLSPSTSSMSANQALSSLKAVGPPPAtPPRKHRGLLATQQAEPSPPSILVTPSEHKSFVPDTGTLtPTSSPQGVKPAPSSSSLYMVTSFVSAPPDPQPPAPEPPPEPTKVTVRSLSPAKEVVSS--------PTPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGRHVLHLDIKPDNLLLAADNALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVRGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP
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Consensus	MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGRGALVAG-GAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVRDSETAEDDISDVQGTQRLELRDDRAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSIPQSGLRREEPDLQPQLASDALRRRPAQPPPSKSALLPPPSPRVGKRALPGPPAQPAATPTSPHRRTQEPSLPEDITTTEEKRGKKPKSSGPSLAGTAESRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAAWGTPGASQEELRAPRGSVAERRRLFQQKAASLDERTRQRSAASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPPPSGAEKPGDEPGRPRSRGPAGRTEPGEGPQQEIRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEDAALPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLIRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDSGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPADVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARLDCKISGTPPPSVTWTHFGCPMNESENLRLRQDGGLHSLHIARVGSEDEGLYAVSATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGDLERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDIHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSSSGKSSSKPSAPSEPVQLLEHGPPLEEAPAMLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDLGALTCSARNRHGTQACSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLAESNHVSFVYEENECSLVVLSAGAQDGGVYTCTARNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRRQPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPEAGAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPPSPARPSAPKPSIPKSAEPSATTPRDAPQPPAPQPAQDKAPEPRPEPVRAAKPAQPPQALQMLAQPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSARGPPVLAEKARVPTVPPRPGSSLSGSIENLESEAVFEAKFKRSRESPLSRGLRLLSRSRSEERGPFRGAEEDDGIYRPSPAGTPLELVRRPERSRSVQDLRAAGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRHRWGLSRLRKDKGLSQPNLSASVQEDLGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPRISWMKDKQSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTQLPVGVTVRFRVACANRAGQGPFSNPSEKVFIRGTQDSPAQPAAAHRDAPVTSRPARARPPDSPTSLAPPLALAAPTPQASTLSPSSPPMPANQALSSLKAVGPPPATPPRRHRGLQAARQAEPSLPSIHVTPSEPKPFVLDTGTLIPASSPQGVKPAPSSTPLYMVTSFVSAPPAPQPPAPEPPPEPTKVTVRSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAADNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP

Multiple Sequence Alignment:
SPEG	Download MSA