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SRPK1 human	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERk K4-ac K4-ub VLALQARkkRTkAKKDKAQRKsEtQHRGsAPHsEsDLPEQEEEILGsDDDEQEDPNDyCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKsAEHyTETALDEIRLLKSVRNsDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGsAVstAPQPKPADKMSKNKKKKLKKKQKRQAELLEkRMQEIEEMEKESGPGQKRPNKQEEsEsPVERPLKENPPNKMtQEKLEEssTIGQDQTLMERDTEGGAAEINCNGVIEVINyTQNSNNEtLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTsQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPkNAEKLKVkIADLGNACWVHk K506-ac K506-ub HFTEDIQtrQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHsGEEYTRDEDHIALIIELLGKVPRkLIVAGk K585-ac K585-ub YskEFFTKKGDLKHITKLkPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS
SRPK1 iso3 human	MERKGERWSGLRHEGQWsPGRGPGQRRELRLTAAVRFPDVRRPSTEVAPPHTPCLWAAGPRPSFRASSGAGRSRPLFPARPARALGPLQGPALGGRRRPPPARPLTRPETPPAHPARALLCAPWAASPTPAASPSPQPPPRQAPQPGLAPLLGLHPHLGRLLSSTFALHPSLSPAVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS
SRPK1 mouse	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKKDKAQRKPETQHRGsAPHSEsDIPEQEEEILGsDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKEsGPGQKRPNKQEEsEsPVDRPLTENPPNKMTQEKLEESNsIGQDQTLTERGGEGGAPEINCNGVIGVVNYPENSNNETLRHKEDLHNANDCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTAS---ETMVCQSSAEQS--LTRQDItQLEEsIRADtPsGDEQ--EPNGALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQtRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS
SRPK1 rat	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGsDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEEsEsPVERPLTENPPNKMTQEKLEESSSIGQDQTLTEHGGEGGAPEINCNGVIGIVNYTANSNNETLRLKEDLHNANDCDGRTLKQEPSFLSSPNGDSSPSPETDSCTPSGSEVPETMACQASVERSLTLTQQDITHLQERIRAHtPsGDEQEREHNGALDSKGKFSAGNFLINPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS
	::::*********************:**************:***************************************************************************************************:****************************************************************************************************************************************************************************:***:***************::*******:*:::****:********:::**::********:***********:.:*:**:***:*.*****:*::******.:*::.:**:**:*::.:..::.*:*::*:*:***.:*::***:.*:**:**:***::*****:***********:*****************************************************************:**************************************************:*********:*****************:******************
Consensus	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKVLALQARKKRTKAKKDKAQRKPETQHRGSAPHSESDIPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSSIGQDQTLMERDGEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQEPSFLSSQNGDSSPSQETDSCTPITSEVSDTMVCQSSSEVGQSLSEQDISQLQESIRAEIPCEDEQEQEHNGALDNKGKFSAGNFLINPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS