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RIPK1 human	MQPDMsLNVIKMKssDFLEsAELDsGGFGKVsLCFHRtQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLAsFKMWsKLNNEEHNELREVDGTA-KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIIsLMKLCWEANPEARPTFPGIEEKFRPFYLsQLEEsVEEDVKsLKKEYsNENAVVKRMQsLQLDCVAVPssRsNsAtEQPGSLHssQGLGMGPVEEsWFAPSLEHPQEENEPSLQSKLQDEANyHLyGsRMDRQTKQQPRQNVAYNREEERRRRVsHDPFAQQRPyENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLyQNNGLyssHGFGTRPLDPGtAGPRVWyRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKyTIyNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQsQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSsLIYVSQN
RIPK1 iso2 human	MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE----------------------------------------------IADLGLASFKMWSKLNNEEHNELREVDGTA-KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
RIPK1 mouse	MQPDMSLDNIKMAssDLLEKTDLDsGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVAsFKTWsKLtKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICtEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEyPDQsPVLQRMFsLQHDCVPLPPsRsN--SEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASyHAFGIFAEKQTKPQPRQNEAYNREEERKRRVsHDPFAQQRARENIKSAGARGHsDPSTTSRGIAVQQLSWPATQ---TVWNNGLYNQHGFGT-------TGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPYFSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPP----NNTCKEESTSRHQAIFDNTTSLTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRIDLLNHLIRASQS
RIPK1 rat	MQPDMSLDNIKMASDDLLERKDLDSGGFGKVSLCFHRTHGFVILKKVYTGPNRAEYNEALLEEGKMMHRLRHDRVVKLLGIIIEEGNYSLVMEYMEQGNLMHVLKTKESVPLSVKGRIIVEIIEGMHYLHDEGVIHKDLKPENILVDRDFHIKIADLGVAsFKTWsKLTKEEHNKQREASSVT-KKNGGTLYYMAPEHLTDINTKPTEKSDVYSFAIVLWAIFANKEPYENVICTEQFLVCINSGNRPNVEDILEFCPREIISLMERCWQTNPEDRPTFFGIEKEFKPFYLSQFEEYVEEDVASLKKEYPSQsPVLKRMFsLQHDCVPLPPSRSN--SEQPGSLHSSQGLPMGPVEESWFSSSPEYPQEENERSVQAKLQEEASYHAFGIFAEKQTKSQPRLNEAYNREEERKRRVsHDPFAQQRVHENVKSAGAKGLPYPSTTSHGNAAHQLSGPASQIKVPLWNNGVYNHHGFGA-------TGTGVWYGPSVSQSYNAYKTPVPETNLPGsIPTMPYISLAPPDDSIRCTIYNSSRVQIGNYNYMDLGPSSQPP----TNTCKVESTSRHQAVFANTTSLTDKHLNPIRENMGKQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRTDLLNQLIQASQS
	*******::***:*:*:**.::************:**::*::*:*:**:***::*:**:****:***:****:*******:*****:*********:********:....:::.:::::.::::::.:::..:::::::::::::::.:::::*****:****:****::*::*:::*::::: *:*************:*:*:***********::*******:******:**::*::.**:*****:*::*:*:*********::**:::**:****.***::*:*****::**:*****:******:.:::*::**:***:***::*:****..:************.*********::*:*:**:**::*:*:***:**:**::*:::::***.***:*:********:************:.**.::::::*.:::*::*:*:*::*:*::::*..:..:***:*:.****:.......:*::***.*..*::::::::******.:*::****:.*::::*::*::**:**:::***::***::*..*:::....::::*:*:::::**:*:*******:**:*****:*::***********:**************************:****:***************:*:***:.**.:**:
Consensus	MQPDMSLNNIKMASSDLLESADLDSGGFGKVSLCFHRTQGLMILKKVYKGPNRAEHNEALLEEAKMMNRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKAEESVPLSVKGRIIVEIIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGLASFKMWSKLNNEEHNEQREVDGTA-KKNGGTLYYMAPEHLNDINAKPTEKSDVYSFAIVLWAIFANKEPYENAICEQQLIMCIKSGNRPNVDDILEYCPREIISLMERCWQANPEARPTFPGIEEEFRPFYLSQLEESVEEDVASLKKEYPNQNAVLKRMQSLQHDCVALPPSRSNSASEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENERSLQAKLQDEANYHAFGIRADRQTKQQPRQNEAYNREEERRRRVSHDPFAQQRPYENFQNAEAKGTAYPSAASHGNAVHQLSGLASQPQVLYQNNGLYNSHGFGTRPLDPGTAGPRVWYRPIPSQMPSLHNIPVPETNYLGNTPTMPFSSLPPTDDSIKYTIYNSSGIQIGAYNYMDIGGTSQPLLDSTNNNCKEEPAARHQAIFDNTTSLTDKHLNPIRENLGKQWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWLMREGIKGATVGKLAQALHQCCRIDLLNSLIYASQN