Multiple Sequence Alignment:
MEK2	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 )
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MEK2 human	MLARRkPVLPALtINPTIAEGPsPTsEGAsEANLVDLQKkLEELELDEQQkKRLEAFLtQkAkVGELkDDDFERISELGAGNGGVVTkVQHRPsGLIMARkLIHLEIk K108-ub K108-sm PAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAkRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVkPsNILVNSRGEIkLCDFGVsGQLIDs S222-p S222-ac MANs S226-p S226-ac FVGtRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVdGEEGEPHsIsPRPRPPGRPVs-GHGMDsRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIkNPAERADLkMLTNHTFIkRsEVEEVDFAGWLCkTLRLNQPGtPtRtAV
MEK2 mouse	MLARRKPVLPALTINPTIAEGPsPt sEGAsEANLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERIsELGAGNGGVVTkARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVkPSNILVNSRGEIKLCDFGVsGQLIDsMANsFVGTRSYMsPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHsVsPRPRPPGRPIsVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLkLLMNHAFIKRSEGEEVDFAGWLCRTLRLKQPs tPtRTAV
MEK2 rat	MLARRKPVLPALTINPTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVkPSNILVNSRGEIKLCDFGVSGQLIDsMANsFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVsPRPRPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKRSEGEDVDFAGWLCRTLRLKQPs tPTRTAV
MEK2 chicken	MPAKRKPVLPALTITPSPAEGPGPG--GSAEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSKELEAIFGRPVVDGAEGESHSVSPWARPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRAAV
MEK2 cow	MLARRKPVLPALTINPAIAEGPSPTSEGASEAHLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEAIFGRPMVDGAEGEPPSISPRPRPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRTAV
	::*********:::***:::::::********:*:**********************************:::****************:****************************************************:**************************************************************:*********************::*****:*:::::::::***: **************************::.*******************:::***::******:::**:
Consensus	MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEAIFGRPVVDGAEGEPHSVSPRPRPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRTAV

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.