Multiple Sequence Alignment:
CDK6	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 )
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CDK6 human	MEk K3-ac K3-m1 K3-ub DGLCRADQQyECVAEIGEGAyGk K26-ac K26-ub VFkARDLKNGGRFVALk K43-ac K43-ub RVRVQtGEEGMPLsTIREVAVLRHLEtFEHPNVVRLFDVCTVsRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLkPQNILVTsSGQIkLADFGLARIYSFQMALtSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGs sDVDQLGkILDVIGLPGEEDWPRDVALPRQAFHSkSAQPIEk K264-ac K264-ub FVtDIDELGkDLLLkCLTFNPAkRIsAy sALsHPyFQDLERCkENLDSHLPPsQNTSELNtA
CDK6 mouse	MEKDSLSRADQQYECVAEIGEGAyGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSdVDQLGKILDIIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSHLPSNQsTSELNTA
CDK6 rat	MEKDSLSRADQQyECVAEIGEGAyGKVFKARDLKNGGRFVALkRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAELFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLHSHLSSSQsTSELNTA
	***::****************************************:*************************************************************************************************************************************************************:*****************:******************************************************::********::.::::*******
Consensus	MEKDSLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSHLPSSQSTSELNTA

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.