Multiple Sequence Alignment:
CDK4	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 )
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CDK4 human	MATSRYEPVAEIGVGAyGTVYkARDPHSGHFVALkSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLrTYLDkAPPPGLPAETIkDLMRQFLRGLDFLHANCIVHRDLkPENILVTSGGTVkLADFGLARIYSYQMALtPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRkPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLtFNPHkRISAFRALQHSYLHkDEGNPE
CDK4 mouse	MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALtPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPREVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEEsDAE
CDK4 rat
	::***********************************::*:******************************:*****:*************:*******:********************:*************************************************************************************:****:********************************************::::*
Consensus	MAASRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNAE

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using MAFFT. Conservation and consensus calculated using von Neumann entropy from PFAAT.