Multiple Sequence Alignment:
CDK1 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300   )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |   
CDK1 human MEDytkIEkIGEGtyGVVykGRHkTTGQVVAMkkIRLEsEEEGVPsTAIREISLLkELRHPNIVSLQDVLMQDSRLyLIFEFLSMDLKkYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLkPQNLLIDDkGtIkLADFGLARAFGIPIRVytHEVVTLWYRsPEVLLGsARYSTPVDIWSIGTIFAELATKkPLFHGDsEIDQLFRIFRALGtPNNEVWPEVEsLQDYkNtFPkWkPGsLASHVkNLDENGLDLLskMLIyDPAkRIsGkMALNHPyFNDLDNQIkkM------
CDK1 iso2 human MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK---------------------------------------------------------VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM------
CDK1 mouse MEDYIKIEKIGEGtyGVVyKGRHRVTGQIVAMkKIRLEsEEEGVPSTAIREISLLkELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDkGtIKLADFGLARAFGIPIRVytHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKkPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALkHPYFDDLDNQIkkM------
CDK1 rat MEDYIKIEKIGEGtyGVVyKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM------
CDK1 chicken MEDYTKIEKIGEGtyGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRSPEVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPDVESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRIsGKMALNHPYFDDLDKSTLPANLIKKF
CDK1 fruit fly MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN------
  ***::*****************:::***:**********::*****************:*:***:*:****:::*:**************:*::*:::::::::*:::::::::::::::::::::::::::::::::::.:::::::::::::::.:::::::******:*******::**:********:****:**:****:**********:**:*:**::::**:*:**:*******:*::::*:::::***::*:**::***:***::***:*::*:****::::::::::      
Consensus MEDYTKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM------
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.