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Akt1 human	-----------------------------------------------------------------------------------------------------MsDVAIVkEGWLHk K14-m1 K14-ub RGEYIkTWRPRYFLLkNDGtFIGYkERPQDVDQR--EAPLNNFSVAQCQLMKtERPRPNtFIIRCLQWTTVIERtFHVEtPEEREEWTTAIQTVADGLKKQEEEEMDFRsG---------SPs S126-p S126-gl DNs S129-p S129-gl GAEEME----VsLAkPKHRVtMNEFEYLkLLGkGTFGKVILVKEKATGRYyAMKILKKEVIVAkDEVAHTLTENRVLQNSRHPFLtALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFsEDRARFYGAEIVSALDYLHSEkNVVYRDLk K276-ub K276-sm LENLMLDkDGHIkItDFGLCkEGIk K301-ub K301-sm DGAt T305-p T305-gl MKt T308-p T308-gl FCGt T312-p T312-gl PEyLAPEVLEDNDyGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAksLLSGLLKKDPKQRLGGGsEDAkEIMQHRFFAGIVWQHVyEKkLSPPFk K426-ac K426-ub PQVTSETDtRyFDEEFtAQMItItPPDQDDsMECVDSERRPHFPQFs S473-p S473-gl ysAsGtA------------------
Akt1 iso2 human	---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSG---------SPSDNSGAEEME----VSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA------------------
Akt1 mouse	-----------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLkNDGTFIGYKERPQDVDQR--ESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEEtMDFRsG---------SPsDNsGAEEME----VsLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYyAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLkLENLMLDKDGHIKITDFGLCKEGIKDGAtMKtFCGtPEyLAPEVLEDNDyGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITItPPDQDDSMECVDSERRPHFPQFs S473-p S473-gl ysAsGtA------------------
Akt1 rat	-----------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGtFIGYKERPQDVEQR--ESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDFRSG---------SPSDNsGAEEME----VALAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKtFCGTPEyLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITItPPDQDDSMECVDSERRPHFPQFs S473-p S473-gl YSASGTA------------------
Akt1 fruit fly	MNYLPFVLQRRSTVVASAPAPGSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQTQVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQ-GIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTGPLGSIA--EEPLFPQFSYQGDMASTLGTSSHISTSTSLASMQ
Akt1 cow	-----------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQR--ESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDFRSG---------SPGENSGAEEME----VSLAKPKHRVTMNDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKEVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKtFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMEGVDSERRPHFPQFsYSASATA------------------
	:.::::::::::::::::::::::::::::::::::::::::::..::  :.::::::::::::*:::**:*:*****:***********:**:::**::*::**::*:::*::::*::*:::::         ::::::::*:::    :::::::::**:::**:**:***********::****:::**:********::**********:***::::****::*******:*******:*:******:***:**:*:***:*******:***:****:::::*********:********::*******:*::*:*:***************:*****:******:*******:********:**::**:***:**::***::::***:**:***:***::*****::*:***::*:***.*:*:::::**::*********:*******:***::::::****:::::::::::::*:******::::::
Consensus	-----------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQR--ESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDFRSG---------SPSDNSGAEEME----VSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA------------------