(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400)
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p53 human	---MEEPQsDPsVEPPLsQEtFsDLWkLLPENNVLsPLPsQ---AMDDLMLsPDDIEQWFtEDPGPDEAPRMPEAAPPVAPAPAAPtPAAPAPAPSWPLSSSVPsQkTYQGsYGFrLGFLhSGTAk K120-ac K120-ub SVTCTySPALNkMFCQLAkTCPVQLWVDs S149-p S149-gl tPPPGtRVRAMAIYk K164-ac K164-ub QSQHMTEVVRRCPHHERCsDsDGLAPPQHLIRVEGNLRVEYLDDrNtFrHsVVVPyEPPEVGSDCTTIHYNYMCNSSCMGGMNRrPILTIITLEDSSGNLLGRNsFEVRVCACPGRDRRtEEENLrkk K292-ac K292-ub GEPHHELPPGStk K305-ac K305-ub RALPNNt-SssPQPk K319-ac K319-ub k K320-ac K320-ub K320-sm K320-ne k K321-ub K321-ne PLDGEyFTLQIrGrErFEMFRELNEALELkDAQAGkEPGGsRAHsSHLk K370-ac K370-me K370-m1 K370-m2 K370-m3 K370-ub K370-ne sk K372-ac K372-me K372-m1 K372-ub K372-ne k K373-ac K373-m1 K373-m2 K373-ub K373-ne GQstsRHk K381-ac K381-ub k K382-ac K382-m1 K382-m2 K382-ub LMFk K386-ac K386-m1 K386-m2 K386-ub K386-sm tEGPDsD
p53 iso2 human	---MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQ---AMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNT-SSSPQPKKKPLDGEYFTLQDQTSFQKENC----------------------------------------------------
p53 iso4 human	---------------------------------------------MDDLMLsPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNT-SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKkGQSTSRHKkLMFKTEGPDSD
p53 mouse	MTAMEEsQsDIsLELPLsQEtFsGLWKLLPPEDILPs-----PHCMDDL-LLPQDVEEFF---EGPsEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQKTYQGNYGFHLGFLQSGTAkSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGsRVRAMAIYKKSQHMTEVVRRCPHHERCsDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEyTTIHyKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKkEVLCPELPPGsAk K302-ac K302-ub RALPTCT-SAsPPQkk K317-ac K317-ub kPLDGEyFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSYLk K367-ac K367-ub Tk K369-ac K369-me K369-ub k K370-ac K370-ub GQsTsRHk K378-ac K378-ub k K379-ac K379-ub TMVk K383-ac K383-ub kVGPDsD
p53 iso2 mouse	MTAMEESQSDISLELPLsQETFSGLWKLLPPEDILPS-----PHCMDDL-LLPQDVEEFF---EGPSEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQkTYQGNYGFHLGFLQSGTAkSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGSRVRAMAIYkkSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEVLCPELPPGSAKRALPTCT-SASPPQKkKPLDGEYFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSLQPRAFQ--------ALIkEEsPNC-
p53 rat	---MEDsQsDMsIELPLsQEtFsCLWKLLPPDDILPTTATGsPNSMEDL-FLPQDVAELL---EGPEEALQVS-APAAQEPGTEAPAPVAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAkSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEEHCPELPPGSAKRALPTST-SSsPQQKKKPLDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSYPKTKkGQSTsRHkkPMIKKVGPDsD
p53 rabbit	---MEESQSDLSLEPPLSQETFSDLWKLLPENNLLTTSLNP---PVDDL-LSAEDVANWLNEDPEE--GLRVPAAPAPEAPAPAAPALAAPAPATSWPLSSSVPSQKTYHGNYGFRLGFLHSGTAKSVTCTYSPCLNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKKSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCPELPPGSSKRALPTTTTDSSPQTKKKPLDGEYFILKIRGRERFEMFRELNEALELKDAQAEKEPGGSRAHSSYLKAKKGQSTSRHKKPMFKREGPDSD
p53 green monkey	---MEEPQSDPSIEPPLsQETFSDLWKLLPENNVLsPLPSQ---AVDDLMLsPDDLAQWLTEDPGPDEAPRMSEAAPHMAPTPAAPTPAAPAPAPSWPLSSSVPSQKTYHGSYGFRLGFLHSGTAKSVTCTYSPDLNKMFCQLAKTCPVQLWVDSTPPPGSRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYSDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCHELPPGSTkRALPNNT-SSsPQPkKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGkEPAGSRAHSSHLkSkkGQSTSRHkkFMFkTEGPDsD
	:::::::.:.::::::::::.:::::::.:.:...... . .::**.::::*:::::...:::.:::::::*:::.:*::::*:::***:*::*****:*******:*:***:****:*******:****:.***:**************::***:*:*********:*******************:***************:::**::**:**************:**::*****:********************************:********************:***:::::******:*****:.* ::**::**********:*::::::::*::::::::::::::.:.:::::::::::..:.:::::::::::.:.:.::::::
Consensus	---MEESQSDPSLEPPLSQETFSDLWKLLPENNILPPLPSQ---AMDDLMLSPDDVEQWFTEDPGPDEALRMPEAAAPQAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGNYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCHELPPGSTKRALPNNT-SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD