Multiple Sequence Alignment:
PDHA1	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 )
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PDHA1 human	MRKMLAAVSRVLSGASQk K18-ac K18-ub PASRVLVASRNFANDATFEIk K39-ac K39-ub KCDLHRLEEGPPVTTVLTREDGLk K63-ac K63-ub YYRMMQTVRRMELk K77-ac K77-sc ADQLYk K83-ac K83-ub K83-sc QKIIRGFCHLCDGQ-------EACCVGLEAGINPTDHLItAyRAHGFTFTRGLSVREILAELtGRKGGCAKGKGGsMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRyGMGt sVERAAAs tDy yk K244-ac K244-ub K244-sc rGDFIPGLRVDGMDILCVREATRFAAAyCRSGkGPILMELQTYRyHGHsMsDPGVs yRtREEIQEVRSk sDPIMLLk K321-ac K321-ub K321-sc DRMVNSNLASVEELkEIDVEVRkEIEDAAQFATADPEPPLEELGyHIySSDPPFEVRGANQWIkFKSVS
PDHA1 iso2 human	MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHsMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
PDHA1 iso4 human
PDHA1 mouse	MRKMLAAVSRVLAGSAQKPASRVLVASRNFANDATFEIkKCDLHRLEEGPPVTTVLTREDGLk K63-ac K63-sc YYRMMQTVRRMELk K77-ac K77-sc ADQLYk K83-ac K83-sc QkIIRGFCHLCDGQ-------EACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRyGMGt sVERAAASTDy yk K244-ac K244-sc RGDFIPGLRVDGMDILCVREATKFAAAYCRSGkGPILMELQTYRyHGHsMsDPGVs yRtREEIQEVRSk sDPIMLLk K321-ac K321-ub K321-sc DRMVNSNLAsVEELk K336-ac K336-sc EIDVEVRkEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIk K385-ac K385-ub FKSVS
PDHA1 rat	MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIkKCDLHRLEEGPPVTTVLTREDGLkYYRMMQTVRRMELkADQLYkQkIIRGFCHLCDGQ-------EACCVGLEAGINPTDHLITAYRAHGFTFNRGHAVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRyGMGt sVERAAASTDYYkRGDFIPGLRVDGMDILCVREATkFAAAYCRSGKGPILMELQTYRyHGHsMsDPGVs yRTREEIQEVRSkSDPIMLLkDRMVNSNLASVEELkEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIkFKSVS
PDHA1 pig	-GKMLAAVSRVLSGVAQKPASRVLVASRTFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQ-------EACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRRGGCGKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFICENNRYGMGTsVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHsMSDPGVsYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYCNDPPFEVRGANQWIKFKSIS
	::*********:::**********:**************************************************************** ************************::::****::*********************************************************************:*******************************************:**************************************************************************************************::**************:
Consensus	MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQ-------EACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.