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HePTP human	-----------------------------------------------------------------------------------------------------------------MVQAHGGRSRAQPLTLSLGAAMtQPPPEKTPAKKHVRLQERrGsNVALMLDVRsLGAVEPICsVNtPREVTLHFLRTAGHPLTRWALQRQPPsPKQLEEEFLkIPsNFVsPEDLDIPGHASkDRYkTILPNPQSRVCLGRAQsQEDGDyINANyIRGYDGKEKVYIATQGPMPNTVsDFWEMVWQEEVSLIVMLTQLREGKEkCVHYWPtEEEtyGPFQIRIQDMkECPEYTVRQLTIQYQEERRsVkHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLkARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPsP
HePTP iso2 human	---------------------------------------------------------MGAsFWPIRQ----A-RE-----------QQR-RALsFRQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
HePTP iso3 human	MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAA--RRGGGRKLASWSLLS----P-QRQTDRQTDSWQEAAW-GPQLLQQTSWLSEPPLGPAPHLsMVQAHGGRsRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
HePTP iso4 human	---------------------------------------MNRLGCWPARSLPRSGRGSGQRsLGLGGHPSGPRHPGtPAAKRTWESPGVRARDCPLSTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGsNVALMLDVRsLGAVEPICsVNtPREVTLHFLRTAGHPLTRWALQRQPPsPKQLEEEFLKIPsNFVsPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQsQEDGDyINANYIRGYDGKEKVYIATQGPMPNTVsDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPtEEEtyGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
HePTP mouse	-----------------------------------------------------------------------------------------------------------------MVQACEGRSRAQLPTLSLGADMTQPPPTKAPAKKHVRLQERRGSSVALMLDVQSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPsPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQsRVCLGRAQsQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQDMKEHPEYTVRQLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVE-TPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPEPNP
HePTP rat	-----------------------------------------------------------------------------------------------------------------MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPsPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVE-TPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP
	...       . . . ..... .      .    .      .  ..  ..    .................****::******::******:******:*:**************:*******:***:****************************:**:********************:*******************************:****:*****************************:*********:**************************:*********:***:******:****:*:*:*******************************::*****::*******************************************************************:***:*::*
Consensus	-------------------------------------------------------------------------------------------------TSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP