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eIF2B-epsilon human	MAAPVVAPPGVVVSRANKRsGAGPGGsGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISkDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIkEHLLkSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAkALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMtMIFkESSPSHPTRCHEDNVVVAVDSTTNRVLHFQkTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVyPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVkERVTLKPRSVLTSQVVVGPNITLPEGsVIsLHPPDAEEDEDDGEFsDDsGADQEKDKVKMkGyNPAEVGAAGkGYLWKAAGMNMEEEEELQQNLWGLKINMEEEsEsEsEQsMDsEEPDsRGGsPQMDDIKVFQNEVLGTLQRGkEENISCDNLVLEINSLKyAYNISLKEVMQVLSHVVLEFPLQQMDsPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDkGQQLRKNQQLQRFIQWLKEAEEEssEDD
eIF2B-epsilon mouse	MAAtAAVP-GAAAGRAsKrGGGG---SGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCHPTSPNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVISNINICRALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVMAVDSATNRVLHFQKTQGLRRFSFPLsLFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGILMNEEVLGNQIHLHVTTREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSTTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVKLKPYCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFsDDsGADQEKEKVKLkGYNPAEVGLEGQGYLWKAEGVNSKEDEELRQSLWGLMIKTEEESETESEGSVDPEELDsRAGsPQLDDIRVFQNEVLGTLQRGREENISCENLVLEINSLKHAYNISLKEVMQVLTLVVLEFPLQQVDGLLDPNRYCALLLPLLkAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSWFSQRDTTDEGQQLRKNQQLQRFIQWLREAEEEssEDD
eIF2B-epsilon rat	MAATAAVP-SAVGGRANKRGGG----SGGGGTQGAEEEPPPPLQAVLVADSFDRRFFPISkDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIkEHLQKSKWCHPTSLNVVRIITSDLYRsLGDVLRDVDAkALVRSDFLLIYGDVVSNINISKALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVLAVDSTTNRILHFQkTQGLRHFSFPLGLFQGSLDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTSREYGARVSNLHMYSAVCADVIRRWVYPLtPEVNFTDSSTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVVGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVILKPHCVLTSQVVVGPDIILPEGSVISLHPPDAEEDEDDGQFsDDsGADQEKEKVKLKGYNPAEVGPEGQGYLWKAEDVDEkEDEELRQSLWGLMINMEEESETESERsVDPEELDsRAGsPQLDDIRVFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQVDGVLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVPSLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWLREAEEEssDDD
eIF2B-epsilon rabbit	MATTVVAPPGAVSDRANKRGGGPGGGGGGGGARGAEEESPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVVSNINVTRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSATNRILHFQKTQGLRRFSFPLSLFQGSGAGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTTREYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTAQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCSITNSVIGPGCCIGDNVVLDRAYLWKGVQVASGAQIHQSLLCDHAEVKEQVTLKPHCVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGQFSDDSGVNQAKEKAKLKGYNPAEVGVAGKGYLWKAADMNTEKEEELRQSLWGLTINEEEESETESERSMDSEELDSRAGSPQLDDIKVFQNEVLGTLQRGKEESISCDNLILEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLEANRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEEFFLEHEALGTCIAKVLMGFYQLEILAEETILSWFGQRDVTDKGRQLRKNQQLQRFIQWLKEAEEEssEDD
	**:::::*.:::..**:**:*:....:****::*****:*************:*****************************************************:*****:***:********:************************:****:****:.:********************:******************.****:***:**********:*:***:*****.:***:***********************************:*:***:******:***::******************************:*****::**:*******************:********:***:****:********:*:********::***:**:**:***********.*****:*.***.:**********:*:*********************:******::*:*:*:*:*********.:*:******::::.:::***:*:****.*:.*****:***.*:*:**:***:****:***:*************:**:***:**:*******:*************::*********:*:.*:::****************:******************:******:*:.:.*****:****************:***.**:*:***************:*******:**
Consensus	MAATAAAPPGAVAGRANKRGGGG-GGSGGGGARGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSATNRILHFQKTQGLRRFSFPLSLFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTTREYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVTLKPHCVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGAAGQGYLWKAADMNEEEDEELRQSLWGLMINMEEESETESERSMDPEELDSRAGSPQLDDIRVFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDGPLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGTSMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLREAEEESSEDD