Multiple Sequence Alignment:
NPM1 Download MSA
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NPM1 human MEDsMDMDMsPLRPQNyLFGCELkADkDyHFkVDNDENEHQLsLrTVsLGAGAkDELHIVEAEAMNyEGsPIkVtLAtLkMsVQPtVsLGGFEItPPVVLrLKCGsGPVHIsGQHLVAVEEDAEsEDEEEEDVkLLsIsGkRsAPGGGskVPQkkVkLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEkAPVkKsIrDtPAkNAQKsNQNGkDskPsstPRskGQEsFkkQEKtPKtPkGPssVEDIkAkMQAsIEkGGsLPkVEAkFINyVkNCFRMtDQEAIQDLWQWRksL
NPM1 iso2 human MEDSMDMDMSPLRPQNYLFGCELKADKDyHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEItPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLsISGkRsAPGGGSkVPQkkVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK-----------------------------KGQEsFkKQEKTPKtPKGPSSVEDIKAKMQASIEKGGSLPKVEAkFINYVKNCFRMtDQEAIQDLWQWRKSL
NPM1 iso3 human MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQAsIEkAH-----------------------------------
NPM1 mouse MEDsMDMDMsPLRPQNyLFGCELKADkDyHFkVDNDENEHQLsLRTVsLGAGAkDELHIVEAEAMNyEGsPIKVtLATLKMsVQPTVsLGGFEItPPVVLRLKCGsGPVHIsGQHLVAVEEDAEsEDEDEEDVKLLGMsGkRsAPGGGNkVPQkkVKLDEDDEDDDED-DEDDEDDDDDDFDEEEtEEKVPVKKsVRdtPAKNAQKSNQNGkDLKPs-TPRskGQEsFkkQEKtPKtPkGPssVEDIkAkMQAsIEkGGsLPkVEAkFINYVkNCFRMTDQEAIQDLWQWRKSL
NPM1 rat MEDsMDMDMsPLRPQNYLFGCELKADkDYHFkVDNDENEHQLSLRTVSLGAGAkDELHIVEAEAMNyEGsPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGsGPVHISGQHLVAVEEDAEsEDEDEEDVKLLGMsGkRSAPGGGNkVPQkKVKLDEDDDEDDED-DEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGkDLkPS-TPRSkGQESFkKQEKTPKtPkGPSsVEDIkAkMQAsIEkGGsLPKVEAkFINYVKNCFRMTDQEAIQDLWQWRKSL
NPM1 iso2 rat MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDDEDDED-DEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKPS-TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEkAH-----------------------------------
  ********************************************************************************************************************************:*******::**********:*********::*:::**:*.::***********:**:***:***::.:::::::::::::::::.:::.::::***********************************:::::::::::::::::::::::::::::::::::::
Consensus MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGISGKRSAPGGGNKVPQKKVKLAADDDDDDDDEDDDDEDDDDDDFDDEEAEEKAPVKKSVRDTPAKNAQKSNQNGKDLKPS-TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.