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K8 human	----------------------------MsIRVtQk K8-ac K8-m1 K8-ub syk K11-ac K11-m1 K11-ub K11-sm Vs S13-p S13-gl ts S15-p S15-gl GPr R18-m1 R18-m2 AFssrsytsGPGsrIssssFsrVGss--NFr R47-m1 R47-m2 GGLGGGy----GGAsGMGGItAVtVNQsLLsPLVLEVDPNIQAVRtQEkEQIktLNNk K101-ac K101-m1 K101-ub K101-sm FAsFIDk K108-ac K108-ub VRFLEQQNk K117-ac K117-ub MLETk K122-ac K122-m1 K122-ub WsLLQQQk K130-ac K130-ub K130-sm tARsNMDNMFEsyINNLRRQLETLGQEk K158-ac K158-ub LkLEAELGNMQGLVEDFkNk K178-m1 K178-ub yEDEINk K185-m1 K185-ub RtEMENEFVLIk K197-ub K197-sm kDVDEAyMNk K207-ac K207-ub VELEsRLEGLtDEINFLRQLyEEEIRELQSQIsDtsVVLsMDNsRsLDMDsIIAEVkAQyEDIANRsRAEAEsMyQIk K285-ac K285-m1 K285-ub K285-sm yEELQsLAGk K295-ac K295-ub HGDDLRRtk K304-ub K304-sm tEIsEMNRNIsRLQAEIEGLk K325-ac K325-ub K325-sm GQRAsLEAAIADAEQRGELAIk K347-ac K347-ub DANAk K352-ac K352-ub LsELEAALQRAkQDMARQLREyQELMNVKLALDIEIATYRk K393-ac K393-ub K393-sm LLEGEEsRLEsGMQNMsIHtKttsGyAGGLssAyGGLtsPGLsysLG---SsFGsGAGsssFsRtsssRAVVVkk K465-ac K465-ub IEtRDGk K472-ac K472-ub K472-sm LVs S475-p S475-gl EssDVLPk
K8 iso2 human	MNGVSWSQDLQEGISAWFGPPASTPASTMSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSS--NFRGGLGGGY----GGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLG---SSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK
K8 mouse	----------------------------MsIRVTQKsYkMstsGPrAFssRsFtsGPGARIssssFsRVGsssssFRGSMGTGVGLGGFGGAGVGGITAVTVNQSLLsPLkLEVDPNIQAVRTQEkEQIKSLNNk K107-ac K107-ub K107-sc FAsFIDkVRFLEQQNkMLETk K128-ac K128-ub WsLLQQQkTSRSNMDNMFESYINNLRRQLEALGQEkLKLEAELGNMQGLVEDFKNkYEDEINkRTEMENEFVLIkkDVDEAyMNkVELEsRLEGLTDEINFLRQIHEEEIRELQSQISDTSVVLsMDNSRsLDMDGIIAEVRAQyEDIANRsRAEAETMYQIKYEELQTLAGkHGDDLRRTktEIsEMNRNINRLQAEIEALk K331-ac K331-ub K331-sc GQRAsLEAAIADAEQRGEMAIk K353-ub K353-sc DAQTKLAELEAALQRAKQDMARQLREYQELMNVKLALDIEITTYRkLLEGEESRLEsGMQNMsIHTKTTSGYSGGLSsSYGGLTsPGFSYGMSSFQPGFGSAGGSNTFSRT--TKAVVVKKIEtRDGk K479-ac K479-ub LVsESsDVVsk K490-ac K490-ub
K8 rat	----------------------------MsVRVTQKsYKMsTSGPRAFssRsFtsGPGARIsSSsFsRVGsssssFRGs------LGGFGGAGVGGITAVTVNQSLLNPLKLEVDPNIQAVRTQEKEQIKTLNNkFAsFIDkVRFLEQQNkMLETkWSLLQQQKTSRSNMDNMFESYINNLRRQLEALGQEKLKLEVELGNMQGLVEDFKNkYEDEINKRTEMENEFVLIKkDVDEAYMNkVELESRLEGLTDEINFLRQIHEEEIRELQSQISDTSVVLSMDNSRsLDMDsIIAEVRAQYEEIANRSRAEAETMYQIkYEELQTLAGkHGDDLRRSkTEISEMNRNISRLQAEIDALkGQRATLEAAIADAEQRGELAVkDANAkLEDLkNALQKAKQDMARQLREYQELMNVKLALDIEIATYRkLLEGEESRLESGMQNMSIHTKTTsGYAGGLSSsYGGLTsPGFSYGMSSFQPGFGSVGGSSTYSRT---KAVVVkKIETRDGkLVsEssDIMsK
	**:********:************:*****:*************..:***:.:.:. ...:*::*:*************:**:*******************:**********************************:********************:*********:***************************************************************::*****************************:*****:****:**********:**********:***********:***********:******::******:*************:*:***::**::*::***:**************************:******************************:*****:********:**:::...::***::**:::***...:********************:.:*
Consensus	----------------------------MSIRVTQKSYKMSTSGPRAFSSRSFTSGPGARISSSSFSRVGSSSSNFRGGLGGGY-LGGGGAAGMGGITAVTVNQSLLSPLKLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLEALGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQIHEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVRAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEALKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYGLGSFQPGFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK