Multiple Sequence Alignment:
MEF2C Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510  )
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MEF2C human MGRKKIQITRIMDERNRQVTFTkRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDkVLLkYTEYNEPHESRtNsDIVEtLRKKGLNGCDsPDPDADDsVGHsPESEDkYRkINEDIDLMISRQRLC-AVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPL----------AHPSLQRNsMsPGVTHRPPSAGNTGGLMGGD-LTS--GA-GTSAGNGYGNPRNsPGLLVsPGN--LNkNMQAksPPP---MNLGMNNRkPDLRVLIPPGSkNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIkSEPVsPPRDRTTTPS-----------------RYPQHT-RHEAGRsPVDSLSSCSSSYDGSDREDHRNEFHsPIGLTRPs-PDEREsPsVKRMRLSEGWAT
MEF2C iso3 human MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAsTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLC-AVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPL----------AHPSLQRNSMSPGVTHRPPSAGNTGGLMGGD-LTS--GA-GTSAGNGYGNPRNSPGLLVSPGN--LNKNMQAKSPPP---MNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLAtPVVSVAtPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLG--------------------------------DRTTTPS-----------------RYPQHT-RHEAGRsPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPS-PDERESPSVKRMRLSEGWAT
MEF2C iso6 human MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGCEsPDPDSS--YALtPRTEEKYKKINEEFDNMIKSHKIP-AVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPL----------AHPSLQRNSMSPGVTHRPPSAGNTGGLMGGD-LTS--GA-GTSAGNGYGNPRNSPGLLVSPGN--LNKNMQAKSPPP---MNLGMNNRKPDLRVLIPPGSKNTMPSV--------NQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPS-----------------RYPQH-TRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPS-PDERESPSVKRMRLSEGWAT
MEF2C mouse MGRkKIQITRIMDERNRQVtFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAsTDMDKVLLKYTEYNEPHESRTNsDIVETLRKKGLNGCDsPDPDADDsVGHsPESEDKYRKINEDIDLMISRQRLC-AVPPPSFEMPVTIPVSSHNSLVYSNPVSTLGNPNLLPL----------AHPSLQRNSMsPGVTHRPPsAGNTGGLMGGD-LTs--GA-GTSAGNGYGNPRNsPGLLVsPGN--LNKNIQAKsPPP---MNLGMNNrKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLSIKSEPVsPPRDRTTTPS-----------------RYPQHTTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPS-PDERESPsVKRMRLsEGWAT
MEF2C iso4 mouse MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGsEsPDPDSS--YALtPRTEEKYKKINEEFDNMIKSHKIP-AVPPPSFEMPVTIPVSSHNSLVYSNPVSTLGNPNLLPL----------AHPSLQRNSMSPGVTHRPPSAGNTGGLMGGD-LTS--GA-GTSAGNGYGNPRNSPGLLVSPGN--LNKNIQAKSPPP---MNLGMNNRKPDLRVLIPPGSKNTMPSV--------NQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGD--------------------------------RTTTPS-----------------RYPQHTTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPS-PDERESPSVKRMRLSEGWAT
MEF2C rat MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDsPDPDTSY--VLtPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPPATLHRNVsPGAPQRPPSTGSAGGMLSTTDLTVPNGAGNGPVGNGFVDSRAsPNLIGNTGANSVGkVMPTKsPPPPGGGSVGMNSRKPDLRVVIPPSSKGMMPPLN-------AQRISSSQATQPLATPVVSVTTPSLPPQGLV--YSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLV-----AGGQLSQGSNLSINTNQNINIKTEPISPPRDRMTPSGFQQQQQQQPQQQPPPQPPQPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNAEDREsPSVkRMRMD-TWVT
  **************************************************:***********************************:*:**:::*::*****::...:::*::*:**:****::*:*::::::: ::**::*:*:*::**:*:*:*:*:**:*:*::*:*:::          ::*:::::::***:::****:*::**::::: **:  ** ::::***::::*:**:*::::*:  ::*::::*****   :::***:*******:***:**::**::........:***::**::*:********:**:**:**:::::**::*:*:*:***:*****:*:**:::::*:**::::***:**:::::*:*::::......:::.::::....:...::.::.:::::*:*:::                 ::**::.*:*:**********:***********:*::*****:*:**: :::**********::::*:*
Consensus MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALRKKELNGCDSPDPDADDSVGHSPESEDKYRKINEDIDNMISRQRIC-AVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPL----------AHPSLQRNSMSPGVTHRPPSAGNTGGLMGGD-LTS--GA-GTSAGNGYGNPRNSPGLLVSPGN--LNKNMQAKSPPP---MNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPS-----------------RYPQHTTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPS-PDERESPSVKRMRLSEGWAT
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.