Multiple Sequence Alignment:
HSP27	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 )
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HSP27 human	MTERrVPFsLLrGPsWDPFrDWyP-HsRLFDQAFGLPrLPEEWSQWLGGSSWPGyVrPLPPAAIEsPA-------VAAPAy sRALsRQLs sGVsEIrHtADRWRVsLDVNHFAPDELTVk tk K114-ub K114-sm DGVVEItGk K123-ac K123-ub HEERQDEHGyIsRCFtRk K141-ac K141-ub y tLPPGVDPTQVSSSLSPEGtLtVEAPMPkLAtQsNEItIPVtFEsRAQLGGPEAAk K198-ub K198-sm sDEtAAk K205-ac K205-ub
HSP27 mouse	MTERRVPFsLLr sPsWEPFRDWYPAHSRLFDQAFGVPRLPDEWSQWFSAAGWPGYVRPLPAATAEGPAAVtL----AAPAFsRALNRQLs sGVsEIRQTADRWRVSLDVNHFAPEELTVkTkEGVVEITGKHEERQDEHGYIsRCFTRkYtLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQsAEITIPVTFEARAQIGGPEAGk sEQsGAK
HSP27 rat	MTERRVPFsLLRsPsWEPFRDWYPAHsRLFDQAFGVPrFPDEWSQWFSSAGWPGYVRPLPAATAEGPAAVTL----ARPAFSRALNRQLs sGVsEIRQTADRWRVsLDVNHFAPEELTVKtKEGVVEITGkHEERQDEHGYISRCFTRKYtLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQSAEITIPVTFEARAQIGGPESEQSG---AK
HSP27 pig	MTERRVPFSLLRSPSWDPFRDWYPAHSRLFDQAFGLPRLPEEWSQWLSHSGWPGYVRPLPPPAIEGPA------AVAAPAYSRLLSRQLsSGVSEIQQTADRWRVSLDVNHFAPEELTVKTKDGVVEITGKHEERQDEHGFISRCFTRKYTLPPGVDPTQVSSSLSPEGTLSVEAPLPKPATQSAEITIPVTFEARAQLGGTEAGKSEKPGTK
HSP27 hamster	MTERRVPFSLLRSPsWEPFRDWYPAHSRLFDQAFGVPRLPDEWSQWFSAAGWPGYVRPLPAATAEGPAAVALAAPLAAPAFHRALNRQLsSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKEGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKTATQSAEITIPVTFEARAQIGGQEAGKSEQSGAK
HSP27 chicken	MAERRVPFTFLTSPsWEPFRDWYH-GSRLFDQSFGMPHIPEDWYKWPSGSAWPGYFRLLPSESALLPA--------PGSPYGRAL-SELSsGISEIRQSADSWKVTLDVNHFAPEELVVKTKDNIVEITGKHEEKQDEHGFISRCFTRKYTLPPGVEATAVRSSLSPDGMLTVEAPLPKPAIQSSEITIPVTVEAKKEEPAKK----------
HSP27 dog	MTERRVPFSLLRSPsWDPFRDWYPAHSRLFDQAFGLPRLPEEWAQWFGHSGWPGYVRPIPPA-VEGPAAAA---AAAAPAYsRALSRQLsSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKDGVVEITGKHEERQDEHGYISRRLTPKYTLPPGVDPTLVSSSLSPEGTLTVEAPMPKPATQSAEITIPVTFEARAQIGGPEAGKSEQSGAK
HSP27 cow	MAERRVPFSLLRGPSWDPFRDWYPAHSRLFDQAFGLPRLPEEWSQWLSHSGWPGYVRALPAAAIEGP------------AYNRALSRQLsSGVSEIQQTADRWRVSLDVNHFAPEELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKSATQSAEITIPVTFQARAQLGGPEAGKSEQPENK
	:****::::*:**:::**:::::::::::::***::::::::::.... .:::::.::::**:::::::*****::**:::*****:*::::*******::::***:::*:.:::*****:::::::::.:::::....::
Consensus	MTERRVPFSLLRSPSWDPFRDWYPAHSRLFDQAFGLPRLPEEWSQWFSHSGWPGYVRPLPAAAAEGPAA-------AAPAYSRALSRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKPATQSAEITIPVTFEARAQIGGPEAGKSEQSGAK

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.