Multiple Sequence Alignment:
K18	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 )
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K18 human	MsFtTR-StFs tNy r sLGsVQAPs yGArPVs S30-p S30-gl s S31-p S31-gl AAsVyAGAGGsGsr R45-m1 R45-m2 IsVs S49-p S49-gl r s t sFr R55-m1 R55-m2 GGMGsGGLAtGIAGGLAGMGGIQNEk K81-ac K81-ub K81-sm EtMQsLNDr R90-ac R90-m1 LAs yLDrVRsLETENRRLEs kIREHLEk K118-m1 K118-ub KGPQ-VRDWsHyFk K131-ac K131-m1 K131-ub IIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVk K167-ac K167-m1 K167-ub K167-sm yETELAMRQsVENDIHGLRk K187-ac K187-m1 K187-ub K187-sm K187-sc VIDDtNItRLQLEtEIEALk K207-ub K207-sm EELLFMk K214-ac K214-ub kNHEEEVkGLQAQIAsSGLTVEVDAPk sQDLAk K247-ac K247-ub K247-sm K247-sc IMADIRAQyDELARkNREELDk yWsQQIEESTTVVTTQSAEVGAAETTLTELRRtVQsLEIDLDsMRNLk K317-ac K317-ub K317-sm K317-sc AsLENsLREVEARyALQMEQLNGILLHLEsELAQTRAEGQRQAQEyEALLNIk K370-ac K370-ub Vk K372-ac K372-ub K372-sm LEAEIAt yRRLLEDGEDFNLGDALDs sNsMQtIQkTtTRRIVDGk K417-ac K417-ub K417-sm K417-sc VVsEtNDtk K426-ac K426-m1 K426-ub K426-sm K426-sc VLRH
K18 mouse	MSFTTRs t tFsTNyRSLGSVRtPSQRVrPAs sAAsVyAGAGGsGs rISVSRSV-WGGsVGs--------AGLAGMGGIQTEKETMQDLNDRLAsYLDkVKSLETENRRLEsKIREHLEKKGPQGVRDWGHYFkIIEDLRAQIFANsVDNARIVLQIDNARLAADDFRVkYETELAMRQsVESDIHGLRk K180-ac K180-ub VVDDTNITRLQLETEIEALkEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPk sQDLSk K240-ac K240-ub IMADIRAQYEALAQkNREELDkYWSQQIEESTTVVTTkSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENsLGDVEARYKAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIkVKLEAEIATYRRLLEDGEDFsLNDALDsSNsMQtVQkTTTRKIVDGRVVsETNDTRVLRH
K18 rat	MSFTTRs tTFSTNYRSLGsVRTPSQRVRPAs sAAsVyAGAGGsGSRISVsRSV-WGGsVGS--------AGLAGMGGVQTEKETMQDLNDRLAsYLDKVKNLETENRRLESkIREYLEkRGPQGVRDWGHYFkTIEDLRAQIFANsVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRkVVDDtNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSkIMADIRAQYEQLAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLLELRRTLQTLEIDLDSMKNQNINLENNLGEVEARYRVQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVkLEAEIATYRRLLEDGDDFsLNDALDSsNSMQTVQRTTTRKVVDGkVVSETNDTRVLRH
	****::********::::::*******************:.::::........:****::****:*******:::************:::::*******:*******************************:****:****************************::******************:******:::*********************::::**:**::*******:::::**:::***::***:**************:***********************:::*********::**:::*****:**
Consensus	MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSV-WGGSVGS--------AGLAGMGGIQTEKETMQDLNDRLASYLDKVKSLETENRRLESKIREHLEKKGPQGVRDWGHYFKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEALAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENSLGEVEARYAAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLNDALDSSNSMQTVQKTTTRKIVDGKVVSETNDTRVLRH

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.