Multiple Sequence Alignment:
ITPKA	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 )
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ITPKA human	MTLPGGPTGMARPGGARPCsPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRrGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIsPFKKRYAWVQLAGHTGsFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVtKPRYMQWREGIsSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER
ITPKA mouse	MTLPGRPTGMARPRGAGPCsPGLERAPRRSVGELrLLFEArCAAVAAAAAAGEPrARGAKRrGGQVPNGLPRAAPAPVIPQLtVTSEE-DVTPASPGPPDQEGNWLPAAG-SHLQQPRRLs tSSLSSTGSSSLLEDsEDDLLsDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMsPFRKRYsWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGIVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTkPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLRRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER
ITPKA rat	MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEE-DVAPASPGPPDREGNWLPAAG-SHLQQPRRLsTSSLSSTGSSSLLEDsEDDLLSDSESRSRGNVQLETSEDVGQkSHWQkIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILkRSSEPEHyCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCkMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKkADGSCSTDFkTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGkTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER
	***.***::******************************************************:*******:.*::****:::::***.*********:***************************::**:*********:::*******************:::**:******:******************************************************************************************************************:**:::***********::******************************************************************:**
Consensus	MTLPGRPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEE-DVAPASPGPPDREGNWLPAAG-SHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLRRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using MAFFT. Conservation and consensus calculated using von Neumann entropy from PFAAT.