Multiple Sequence Alignment:
epsin 2 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640       650         )
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epsin 2 human MtTssIRRQMkNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGkNWRHVYKALTLLDyLIKTGSERVAQQCRENIFAIQTLkDFQYIDRDGkDQGINVREKSkQLVALLkDEERLkAERAQALKtKERMAQVATGMGsNQITFGrGssQPNLsTSHsEQEyGKAGGsPAsYHGsPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLAsRPNGDWSQPCLtCDRAARATSPRVSSELEQARPQtsGEEELQLQLALAMsREVAEQ------------EERLRRGDDLRLQMALEESRRDtVkIPKKKE------HGsLPQQTTLLDLMdALPSSGPAAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNsDPWAASQQPASsAGkRAsDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSLPSQNNGTTsPDPFEsQPLTVASSKPSsARKtPESFLGPNAALVNLDSLVTRPAPPAQSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLRGsPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGsVGIPPsAAQATGTTNPFLL
epsin 2 iso2 human MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEyGkAGGsPAsyHGst---------------------------------------------------------SPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRDtVKIPKKKE------HGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSLPSQNNGTTSPDPFESQPLTVASSKPSSARKTPESFLGPNAALVNLDSLVTRPAPPAQSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVGIPPSAAQATGTTNPFLL
epsin 2 mouse MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLkDFQYIDRDGkDQGINVREKSkQLVALLkDEERLKVERVQALKTKERMAQVATGVGSNQITFGrGssQPNLSTSysEQEyGkAGGsPAsyHGs---------------------------------------------------------TsPRVSSELEQARPQtSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEESRRDtVKVPKKKEAKACCKPGSHSQQTTLLDLMDALPSSGPVTQKTEPWSAGASANQTNPWGGTVAPSNITDPWPSFGTKPAASVDPWGVPTTASTQSVPKNSDPWAASQQPASNAGkT-TDAWGAA---KPSSASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDsRttsPDLFEsQSLtSASSkPSSARKtPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAAA-PAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETV--APMTSVAPHSSVGASGSSLTPLGPTAMNMVGSVGIPPSAAQSTGTTNPFLL
epsin 2 iso3 mouse MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGkAGGsPAsyHGsPEASLCPQHRTGAMLGQSEELQPLSQRHPCLPHLGLASHPNGDWAQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRDTVKVPKKKE------PGSHSQQTTLLDLMDALPSSGPVTQKTEPWSAGASANQTNPWGGTVAPSNITDPWPSFGTKPAASVDPWGVPTTASTQSVPKNSDPWAASQQPASNAGKT-TDAWGAA---KPSSASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDSRTTSPDLFESQSLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAAA-PAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETV--APMTSVAPHSSVGASGSSLTPLGPTAMNMVGSVGIPPSAAQSTGTTNPFLL
epsin 2 rat MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSsQPNLSTSySEQEyGKAGGSPASYHGSPEASLCPQHRTGAMLGQSEELQPLSQRHPCLPHLGLASHPNGDWAQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRDTVKVPKKKEVKACCKPGSHSQQTTLLDLMDALPSSGPVAQKTEPWSTGTPANQTNPWGGTVAPANISDPWPSFGTKPAASVDPWGVPTTASIQSVPKNSDPWAASQQPASDAGKT-ADAWGAA---KPSPASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDsRTTsPDLFESQSLTSASSKPSSARKtPESFLGPNAALVNLDSLVTKPNPPAQSLNPFLAPGAAA-PAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETV--APMPSVAPHSALGATGSSLTPLGPTAMNMVGSVGIPPSAAQPAGTTNPFLL
epsin 2 iso1 rat MTTSSIRRQMKNIVNSYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSISHSEQEYGKAGGsPAsYHGST---------------------------------------------------------SPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRDTVKVPKKKEVKACCKPGSHSQQTTLLDLMDALPSSGPVAQKTEPWSTGTPANQTNPWGGTVAPANISDPWPSFGTKPAASVDPWGVPTTASIQSVPKNSDPWAASQQPASDAGKT-ADAWGAA---KPSPASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDSRTTSPDLFESQSLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAAA-PAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETV--APMPSVAPHSALGATGSSLTPLGPTAMNMVGSMGIPPSAAQPAGTTNPFLL
  ***************:***********************************:*****************************************************************************************:**:***************:*****************:*:******************.........................................................:************************************            *************************:*****......:**::*****************::**:***::::::********::**::::*************:*******:*:.******************.***:.:*****:...**:::*********:***:***************:***::*:*:*:::*****:****:**:******************************:*:**************:*.:**************************:*:***:*****::..*:*:*:**::::**:*********::******:********::********
Consensus MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSPEASLCPQHRTGA-LGQSEELQPLSQRHP-LPHLGLAS-PNGDW-QPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRDTVKVPKKKE-KACCKPGSHSQQTTLLDLMDALPSSGPVAQKTEPWSAGASANQTNPWGGTVAPANISDPWPSFGTKPAASVDPWGVPTTASIQSVPKNSDPWAASQQPASNAGKT-ADAWGAA---KPSSASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDSRTTSPDLFESQSLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAAA-PAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETV--APMTSVAPHSALGATGSSLTPLGPTAMNMVGSVGIPPSAAQATGTTNPFLL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.