	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530)
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EPRS human	MATLSLTVNSGDPPLG------------------ALLAVEHVKDDVsISVEEGKENILHVSENVIFTDVNSILRYLARVATtAGLYGSNLMEHTEIDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLkQKKAPVHVKRWFGFLEAQQAFQSVGTKWDVSTTkARVAPEKKQDVGkFVELPGAEMGkVTVRFPPEASGYLHIGHAkAALLNQHyQVNFk K229-m1 K229-ub K229-sc GkLIMRFDDTNPEkEkEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEk K282-ac K282-ub LIQEGkAYVDDTPAEQMk K300-ac K300-ub AEREQRIDSKHRKNPIEkNLQMWEEMKk K328-m1 K328-ub GsQFGQsCCLRAKIDMs sNNGCMRDPtLyRCkIQPHPRTGNk K370-ac K370-ub YNVYPTyDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRk K417-ac K417-ub PYIWEySRLNLNNTVLs kRkLTWFVNEGLVDGWDDPrFPTVRGVLRrGMtVEGLkQFIAAQGSSRSVVNMEWDKIWAFNk K497-ac K497-ub k K498-ac K498-ub VIDPVAPRYVALLk kEVIPVNVPEAQEEMkEVAKHPk K535-ac K535-ub NPEVGLk K542-ac K542-ub PVWy sPKVFIEGADAETFSEGEMVTFINWGNLNITKIHkNADGkIISLDAkLNLENk K599-ac K599-ub DYKKTTKVTWLAETTHALPIPVICVTYEHLITKPVLGkDEDFkQYVNkNSKHEELMLGDPCLKDLKkGDIIQLQRRGFFICDQPyEPVsPy sCKEAPCVLIYIPDGHTkEMPTsGSKEkTkVEATkNETSAPFkERPTPsLNNNCt t sEDsLVLyNRVAVQGDVVRELKAKKAPKEDVDAAVkQLLSLk K788-ac K788-sc AEYKEKTGQEYKPGNPPAEIGQNIsSNs sASILESKsLyDEVAAQGEVVRKLKAEKsPKAkINEAVECLLsLk K861-ac K861-ub AQyKEKTGKEyIPGQPPLsQs sDs sPtRNsEPAGLEtPEAkVLFDkVAsQGEVVRKLKTEKAPkDQVDIAVQELLQLkAQYk sLIGVEy kPVsATGAEDKDKKKKEKENKSEKQNKPQkQNDGQRKDPsk K991-m1 K991-ub NQGGGLs s sGAGEGQGPkKQtRLGLEAk kEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIk kLGVENCYFPMFVSQSALEKEkTHVADFAPEVAWVTRSGkTELAEPIAIRPTSETVMYPAYAkWVQSHRDLPIkLNQWCNVVr R1152-m1 R1152-m2 WEFk K1156-ac K1156-ub HPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVkGRKTEKEKFAGGDy tTTIEAFISASGRAIQGGTSHHLGQNFSkMFEIVFEDPKIPGEKQFAYQNSWGLTTr tIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLsVNIRVRADLRDNy sPGWkFNHWELk K1361-ub K1361-sc GVPIRLEVGPRDMkSCQFVAVRRDTGEk K1389-ac K1389-ub LTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQkILDSGKIVQIPFCGEIDCEDWIkKTTARDQDLEPGAPSMGAkSLCIPFkPLCELQPGAKCVCGKNPAk K1503-ac K1503-ub YYTLFGrSY
EPRS mouse	MAALCLTVNAGNPPL------------------EALLAVEHVKGDVSISVEEGkENLLRVSETVAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTkWDVSGNRATVAPDKKQDVGKFVELPGAEMGkVTVRFPPEASGYLHIGHAKAALLNQHYQVNFkGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMkAEREQRTESKHRKNsVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLyRCkIQPHPRTGNKYNVYPTyDFACPIVDSIEGVTHALRTTEyHDRDEQFyWIIEALGIRKPYIWEYSRLNLNNTVLs kRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMtVEGLKQFIAAQGSSRSVVNMEWDKIWAFNkKVIDPVAPRYVALLKKEVVPVNVLDAQEEMkEVARHPk K535-ac K535-ub NPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITsLDAkLNLENKDYKKTTKITWLAESTHALSIPAVCVTYEHLITKPVLGkDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVsPy sCREAPCILIYIPDGHTKEMPTSGSKEKTKVEISKKETSSAPKERPAPAVSSTCATAEDSSVLySRVAVQGDVVRELKAKKAPKEDIDAAVkQLLTLkAEYKEKTGQEYKPGNPSAAAVQTVSTKSSSNTVESTSLYNkVAAQGEVVRKLkAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPGQPPASQNSHSNPVSNAQPAGAEKPEAKVLFDRVACQGEVVRKLkAEKASkDQVDSAVQELLQLk K939-ac K939-ub AQyKsLtGIEYkPVsATGAEDkDKKKKEKENKSEKQNKPQKQNDGQGKDSSKSQGsGLs sGGAGEGQGPkKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEkNHIEDFAPEVAWVTRSGkTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVrWEFkHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNy sPGWKFNHWELKGVPVRLEVGPRDMkSCQFVAVRRDTGEkLTIAEk K1395-ac K1395-ub EAEAKLEkVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQk K1435-ac K1435-ub VLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAPsMGAKSLCIPFNPLCELQPGAMCVCGKNPAKFYTLFGRSY
EPRS rat	MAALCLTVNAGNPPLGCRVKVNKRNKSFMLSFLEALLAVEHVKGDVSISVEEGKENLLRVSESVVFTDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKELNHCLsLRTYLVGNSLTLADLCVWATLKGNAACQEHLRQSKTLVHVNRWYGFLEAQQAFRSVGTKWDASANKATGAPDRKQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEkEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEkLIEEGKAYVDDTPADEMKAE------------PVEKNLQMWEEMKRGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRkPYIWEYSRLNLNNTVLsKRKLTWFVNEGL--------------------------------GSSRSVVNMEWDKIWAFNKkVIDPVAPRYVALLKKEVIPVNILDAQEEMkEVARHPkNPDVGLkPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNPDGKITSLDAKLNLENkDYKKTTKITWLAETTQALPVPAVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISKKETGSAPKERPAAAVsAPCAAAEDAAILy sRVAVQGDAVRDLKAKKAPKEDIDAAVKQLLTLkAEYKEKTGQEYRPGNPPTAAVQTVSTKsPSNTGEYTSLYNKVAAQGELVRKLKAEKAPKAKINDAVECLLSLkAEYKEKTGKEYVPGQLPASQNSHSSPVSNAKPVGSETPEAKLLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLkAQYKSLTGIEYkPVSATGAEDKDKKKKEKENKSEKQNKPQKQNDGQGKDSSKSQGsGLsSGGAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQGALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFkHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTLEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITNTLSEEDREALMAKCNEYRRRLLGADIRARVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEkLTIAEkEAESKLKGVLEDIQLNLFTRASEDLKSHMVVSDTLEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQDVEPGAPsMGAKSLCIPFNPLCELQPGAMCVCGKNPAKFYTLFGRSY
	*::***::*:.................:*****:*********::**.:*:******:::*:*******************.:::**************:********::*::.::*::*******:****:::::::::************************************************************************************************:*******::::::..::::::::*******:******************************************************************************************************************::::::::::::::::::::::::::::::::*********************************::::******:*:*******************************:****::**************:**::*::::********************::******************************************::*********************:::::::*::::::.:::::::*****::********:****:*********:*:::::::::::::.::::**:****::::******:****::**::*::::::.:::**:::******::**:************::***********************************::::**:*********************:***********::********::*:****************::***:::********************************************::*******************************::**::********:*************:*********:********:****:*****:********.************::***:*::*:**:::::******************:**********************::*:.::***::******:*:::***::::************:**:************:*****:*****:******
Consensus	MAALCLTVNAGNPPLG-----------------EALLAVEHVKGDVSISVEEGKENLLRVSENVAFTDVNSILRYLARVATTSGLYGSNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGNAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSANKATVAPDKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVALLKKEVIPVNVLDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWLAETTHALPIPAVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISKKETSSAPKERPAPAVSANCATAEDSAVLYSRVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPPAAAVQTVSTKSSSNTGESTSLYNKVAAQGEVVRKLKAEKAPKAKINEAVECLLSLKAEYKEKTGKEYVPGQPPASQNSHSSPVSNAQPAGAETPEAKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATGAEDKDKKKKEKENKSEKQNKPQKQNDGQGKDSSKSQGSGLSSGGAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLQAVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCVCGKNPAKFYTLFGRSY

Multiple Sequence Alignment:
EPRS	Download MSA