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SREC-II human	MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGyFGANCDtKCPRQFWGPDCKELCsCHPHGQCEDVtGQCtCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGtYGEDCAFVCADCGSGHCDFQsGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTrRPRPrRELsLGRKKAPHRLCGRFSRIsMkLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPsPSWSSRAsFSSFDTTDEGPVyCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDsERsASSVEGPGGALyARVARREARPARARGEIGGLsLsPsPERRKPPPPDPATkPKVSWIHGKHSAAAAGRAPsPPPPGSEAAPsPSKRKRtPsDKsAHTVEHGsPRTRDPTPRPPGLPEEATALAAPsPPRARARGRGPGLLEPTDAGGPPRSAPEAASMLAAELRGKTRsLGRAEVALGAQGPREKPAPPQKAKRSVPPAsPARAPPAtEtPGPEKAAtDLPAPEtPRKKTPIQKPPRKKsREAAGELGRAGAPtL--
SREC-II iso2 human	MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTR-----RELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARAAPRP-LGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRKKSREAAGELGRAGAPTL--
SREC-II mouse	MEGAGSRGAGPARRQGARG--------LGLLLLLWLLPGLAAPQDLNPRGRNVCRTPGSQVLTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHVGWWGRSCNNQCACNSSPCEQQSGRCQCRERMFGARCDRYCQCSHGRCHPVDGTCACDPGYRGKYCREPCPAGFYGPGCRRRCGQCKGQQPCTVVEGRCLTCEPGWnGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSnGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRkGVMGAGALLTLLLGLLLSLLGCCCACRGKDSA-----RRELTLGRKKAPQRFCGsFSRIsMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLDPPSGLEQPSPSWSSRAsFSSFDTTDEGPVYCVPHEEATADSRDLEATAALTEVAAVSLEPTGTSTPGEEAAVLPASSDSERSASSVEGPSGALyARVARREARPARTRNEAGGLsLsPsPERRKPPPPDPATKPKVSWIHGKHSAAAA--APsPPPAGRKAAPsPSGRKRtPsNss---------------VQPPGLtEEAPGPAsPtPPRARARGrGLGLSEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRA----------EKPPPPQKAKRSVLPAATVRTASASEASGSEKAAASAPAPETPRKKTPIQKPPRKKsREAAGEPSRAGTAPGAS
SREC-II rat	MEGAGSRGAGPARRQGARG--------PPLLLLLWLLPGLAAAQDLNPRGRNVCRTPGSQVLTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCSCNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACDPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVVEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGAGALLTLLLGLLLSLLGCCCACRGKDSA-----RRELTLGRKKAPQRFCGSFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEATAENRDPEASASLTEVPAVSLAPMGTSVPGDEAAALPASSDSERSASSVEGPGGALYARVARREARPARTRCEAGGLSLsPsPERRKPPPPDPATKPKVSWIHGKQGAVAA--APsPPPAGRKAAPsPSGRKRTPSNMS---------------VQPPGLTEEATGPASPTPPRARARGRGPGLLEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRA----------EKPPPPQKAKRSVLPASTARAASASEASASEKVAASAPEPETPRKKTPIQKPPRKKSREAAGEPSRAGAAPGAS
	*****:********:**:*........:.******:**:::*:*:**********:*****:********:*****************************************************:******************************************************************************:***********:******************:***********::************:******************:*****************:*****************************:********************:***************************:******************************:****:**********::*************************:**::****************::.    :***:*******:*:**:*************************************:*************************************:*::**:*:.::::*::*:*::*.:*:::::**::*****************:****************:*.*:*******************************::*:**..******:*::******:******:.*...............::****:***:::*:*:*******:::.:::::::::::*::::********::*:********..........***:*********:**:::*:::*:*::::**:*:::*:************************::***::::..
Consensus	MEGAGPRGAGPARRRGARGPPSPLLPSLLLLLLLWLLPDLAAPQDLNPRGRNVCRAPGSQVLTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACDPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGADCAQACSCHEDSCDPVTGACHLETNQRKGVMGAGALLTLLLCLLLSLLGCCCACRGKDPAR----RRELSLGRKKAPQRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEAPAVLAEAPAPSLVPLGTPAPAEEAAPLPASSDSERSASSVEGPGGALYARVARREARPARARGEAGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPAGREAAPSPSGRKRTPSNKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARGRGPGLLEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRAEVALGAQGPREKPAPPQKAKRSVLPASPARAAPASEAPGPEKAAADAPAPETPRKKTPIQKPPRKKSREAAGELGRAGAAPGAS