(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540        )
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CCT8 human	MALHVPk K7-ac K7-ub APGFAQMLk K16-ac K16-ub EGAk K20-ac K20-ub HFsGLEEAVyRNIQACk K37-ub K37-sc ELAQTTRTAYGPNGMNkMVINHLEkLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRkAHEILPNLVCCsAk K152-ac K152-ub NLRDIDEVSsLLRTSIMSkQyGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGsGIsSSsVLHGMVFk K224-ub K224-sm k K225-ac K225-ub EtEGDVtsVk K235-ub K235-sc DAKIAVYSCPFDGMItETkGtVLIktAEELMNFskGEENLMDAQVKAIADtGANVVVtGGk K296-ac K296-ub VADMALHyANkYNIMLVRLNsk K318-ac K318-ub WDLRRLCk K326-ac K326-ub tVGAtALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEk K367-ac K367-ub EDGAISTIVLrGstDNLMDDIERAVDDGVNTFk K400-ac K400-m1 K400-ub K400-sc VLTRDKRLVPGGGAtEIELAkQITSyGEtCPGLEQyAIk K439-ac K439-ub k K440-ac K440-ub FAEAFEAIPRALAENSGVk K459-ub K459-sm K459-sc ANEVISk K466-ac K466-ub LyAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTyLGKyWAIKLAtNAAVtVLRVDQIIMAk K528-ac K528-m1 K528-ub PAGGPk K534-ac K534-ub K534-sm PPsGk K539-ac K539-ub k K540-ac K540-ub DWDDDQND
CCT8 iso2 human	-------------------MhFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND
CCT8 mouse	MALHVPkAPGFAQMLk K16-ac K16-ub DGAkHFsGLEEAVyRNIQACKELAQTTRtAyGPNGMNKMVINRLEkLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVISGYEIACKKAHEILPELVCCSAKNLRDVDEVSSLLRTSIMSKQYGSETFLAKLIAQACVSIFPDSGNFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGDVTSVk K235-ub K235-sc DAKIAVYSCPFDGMITETkGTVLIkTAEELMNFskGEENLMDAQVkAIAGTGANVIVTGGkVADIALHyANKYNIMLVRLNskWDLRRLCKtVGATALPKLTPPVQEEMGHCDSVYLSEVGDTQVVVFKHEkEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFk K400-ub K400-sc VLTRDKRLVPGGGATEIELAkQITSYGETCPGLEQYAIKkFAEAFEAIPRALAENSGVk K459-ub K459-sc ANEVISkLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIMAkPAGGPkPPsGkkDWDDDQND
CCT8 rat	MALHVPKAPGFAQMLkDGAKHFSGLEEAVyRNIQACKELAQTTRTAYGPNGMNKMVINRLEk K62-ac K62-ub LFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVITGYEIACKKAHEILPDLVCCSAKNLRDVDEVSSLLRTSIMSKQYGSEEFLAKLISQACVSIFPDSGNFNVDNIRVCKILGSGVYSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADMALHYANKYNIMLVRLNSkWDLRRLCKTVGATALPKLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFkVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISkLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPkPPSGkKDWDDDQND
CCT8 cow	MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRLGLSVSEVIEGYEIACKKAHEILPDLVCCSAKNLRDVDEVSSLLHTSVMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGVHSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKSAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGRVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLNPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGVLDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDEDQND
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Consensus	MALHVPKAPGFAQMLKDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACKKAHEILPNLVCCSAKNLRDVDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND