Multiple Sequence Alignment:
APE1	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 )
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APE1 human	MPkRGk K6-ac K6-m1 k K7-ac K7-ub GAVAEDGDELr tEPEAk K24-ac K24-ub K24-sc k K25-ac K25-ub Sk K27-ac K27-ub TAAk kNDkEAAGEGPALyEDPPDQk K52-ub K52-sm TsPsGk K58-m2 K58-ub PATLkICsWNVDGLrAWIKKkGLDWVk K85-ac K85-ub K85-sm EEAPDILCLQETkCSENkLPAELQELPGLSHQYWSAPsDk K125-ac K125-ub EGySGVGLLSrQCPLKVSYGIGDEEHDQEGrVIVAEFDSFVLVTAyVPNAGRGLVRLEyRQRWDEAFRKFLk K197-ac K197-ub K197-sc GLASRKPLVLCGDLNVAHEEIDLRNPKGNKkNAGFtPQERQGFGELLQAVPLADsFRHLYPNTPyAYTFWTYMMNARSkNVGWRLDYFLLSHSLLPALCDSKIrSKALGSDHCPITLYLAL
APE1 mouse	MPKRGKKA-AADDGEEPKsEPEtKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSPSGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDkEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKkNAGFtPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL
APE1 rat	MPKRGKRA-AAEDGEEPKsEPEtKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSASGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFILVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGEMLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL
	*****::.::*::::*::::****:*******::****************************************************:****************************:**********::*****************************:****************************************:*************:*******************************************************
Consensus	MPKRGKKA-AAEDGEEPKSEPETKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSPSGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.