Multiple Sequence Alignment:
LDH-A Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360    )
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LDH-A human -----------------------------MAtLkDQLIyNLLkEEQ-TPQNkITVVGVGAVGMACAISILMKDLADELALVDVIEDkLkGEMMDLQHGSLFLRtPkIVSGkDyNVTANskLVIItAGARQQEGESRLNLVQRNVNIFkFIIPNVVkysPNCkLLIVSNPVDILTyVAWKISGFPkNrVIGsGCNLDsArFRyLMGERLGVHPLsCHGWVLGEHGDSSVPVWSGMNVAGVSLkTLHPDLGTDkDkEQWkEVHkQVVEsAyEVIk-LkGYtsW-AIGLSVADLAESIMKNLRrVHPVSTMIkGLYGIkDDVFLSVPCILGQNGISDLVkVTLtsEEEARLkksADtLWGIQkELQF
LDH-A iso2 human -----------------------------MATLKDQLIYNLLKEEQ-TPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKECRytLGDPKGAAILKSSDVISFHCLGY-------------NRILGGGCACCPFYLICD-----------------------------------------------
LDH-A iso3 human MGEPSGGYTYTQTSIFLFHAKIPFGSkSNMATLKDQLIYNLLKEEQ-TPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIK-LKGYTSW-AIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
LDH-A mouse -----------------------------MATLkDQLIVNLLkEEQ-APQNKITVVGVGAVGMACAIsILMKDLADELALVDVMEDkLkGEMMDLQHGSLFLkTPkIVSSkDYCVTANSKLVIITAGARQQEGEsRLNLVQRNVNIFkFIIPNIVkYSPHCKLLIVSNPVDILtyVAWKISGFPkNRVIGsGCNLDSARFRyLMGERLGVHALsCHGWVLGEHGDSSVPVWSGVNVAGVSLKsLNPELGTDADkEQWkEVHkQVVDsAyEVIk-LKGYTSW-AIGLSVADLAESIMKNLRRVHPISTMIKGLYGINEDVFLSVPCILGQNGISDVVKVTLtPEEEARLKkSADTLWGIQkELQF
LDH-A rat -----------------------------MAALkDQLIVNLLkEEQ-VPQNKITVVGVGAVGMACAISILMkDLADELALVDVIEDkLkGEMMDLQHGSLFLKTPkIVSSkDYsVTANSKLVIITAGARQQEGESRLNLVQRNVNIFkFIIPNVVkYSPQCKLLIVSNPVDILTYVAWKISGFPkNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGVNVAGVSLKsLNPQLGTDADkEQWkDVHkQVVDSAyEVIk-LKGYTSW-AIGLSVADLAESIMKNLRRVHPISTMIkGLyGIKEDVFLSVPCILGQNGISDVVKVTLtPDEEARLKksADtLWGIQKELQF
LDH-A chicken ------------------------------MSLKDHLIHNVHKEEHAHAHNKISVVGVGAVGMACAISILMKDLADELTLVDVVEDKLKGEMLDLQHGSLFLKTPKIISGKDYSVTAHSKLVIVTAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPDCKLLIVSNPVDILTYVAWKISGFPKHRVIGSGCNLDSARFRHLMGERLGIHPLSCHGWIVGEHGDSSVPVWSGVNVAGVSLKALHPDMGTDADKEHWKEVHKQVVDSAyEVIK-LKGYTSW-AIGLSVADLAETIMKNLRRVHPISTAVKGMHGIKDDVFLSVPCVLGSSGITDVVKMILKPDEEEKIKKSADTLWGIQKELQF
                               :::***:**:*::***: :::***:************************:****:********:*********:****:*:***:***:*****:*****************************:*****.*************************:***************:*******:*:******::*************:********:*:*::***:***:**:::::::::::::*: :::::*: ::*:::::::::::::::*:::::::::::::*:::::::::::::::::::.::::::..:::::::::::::::::::::
Consensus -----------------------------MATLKDQLIYNLLKEEQ-TPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDADKEQWKEVHKQVVDSAYEVIK-LKGYTSW-AIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKDDVFLSVPCILGQNGISDVVKVTLTPEEEARLKKSADTLWGIQKELQF
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.