Multiple Sequence Alignment:
L2HGDH Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460    )
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L2HGDH human MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGS-RSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIyyk
PESLKAKLCVQGAALLYEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEk
GLQNGVPGLrLIQQEDIk
KKEPYCRGLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAkESPSRsIDGMQYPIVIkNTKGEEIRCQYVVTCAGLYSDRISELsGCTPDPRIVPFRGDyLLLKPEKCYLVkGNIYPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFkREGYRPFDFSATDVMDIIINSGLIKLASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFVFDAGVGDIGNRILHVRNAPsPAATSSIAISGMIADEVQQRFEL
L2HGDH mouse MWPTLRYVGGVCGLARYCVAGGFLRASGPASGVPGLLCGGGRRSSSTSSFDIVIVGGGIVGLASARTLILKHPGLSIGVVEKEKDLALHQTGHNSGVIHSGIYYk
PESLKAKLCVEGAALIYEYCNLKGIPYRQCGKLIVAVEQEEIPRLQALYERGLQNGVEGLRLIQQEDIk
KKEPYCRGLMAIDCPYTGIVNYQQVALSFAQDFQEAGGSILRDFEVkGIEIAkENSSRSKDGMNYPIAVKNSKGKEIRCRYVVTCAGLYSDRISELSGCNPDPQIVPFRGDYLVLKPEKGYLVk
GNIYPVPDSRFPFLGVHFTPRLDGTIWLGPNAVLAFkREGYRPFDFDARDVMEVILKSGFINLVFQHFSYGVNEMYKACFLSETVKHLQKFIPEITISDVLRGPAGVRAQALDRDGNLVEDFVFDGGTGEIADRVLHVRNAPsPAATSSLAISRMIAEEAQQRFKL
L2HGDH rat MWPTLRYVGGVCGRIGCSVAGGFLRASGPVSGVLGLLCRGG-RSSSTSSFDIVIVGGGIVGLASARTLILKHPELSIGVVEKEKDLALHQTGRNSGVIHSGIYYKPESLKAKLCVEGAALIYEYCNLKGIPYRQCGKLIVAVEQEEIPRLQALYERGLQNGVQGLRLIQQEDIKKKEPYCRGLMAIDCPYTGIVNYQQVALSFAQDFQEAGGSILKDFEVKDIGIAKEDPPRSKDGMKYPIAVKNSKGKEIQCRYVVTCAGLYSDRISELSGCNPDPQIVPFRGDYLVLKPEKGYLVKGNIYPVPDSRLPFLGVHFTPRLDGSIWLGPNAVLAFKREGYRPFDFNARDIMEVILKSGFIKLVFQNFSYGASEIYKACFLSETVKHLQKFIPEITTNDVLRGPAGVRAQALDRDGNLVDDFVFDGGAGEIGDRILHVRNAPSPAATSSLAISRMIAEEVQQRFKL
  *:*:***::*:**:::..:***:::*:*::**::::**:*:.**:*********************:***:**.*****:*******:****:**********************:****:****::***:*:**********************:******.**************************:****:*:****************:*.:****:*::***.::**:***.***::**:**:**:*:*******************:***:*********:*****:**************:**********:**:*********************.*:*:*::*::**:*:*::*:****:.*:******::***:*********::*:*******************:*****:*:*:*::*:**************:***:***:*:****:*
Consensus MWPTLRYVGGVCGRARCCVAGGFLRASGPASGVPGLLCGGG-RSSSTSSFDIVIVGGGIVGLASARTLILKHPELSIGVVEKEKDLALHQTGHNSGVIHSGIYYKPESLKAKLCVEGAALIYEYCNLKGIPYRQCGKLIVAVEQEEIPRLQALYERGLQNGVQGLRLIQQEDIKKKEPYCRGLMAIDCPYTGIVNYQQVALSFAQDFQEAGGSILRDFEVKGIEIAKENPSRSKDGMNYPIAVKNSKGKEIRCRYVVTCAGLYSDRISELSGCNPDPQIVPFRGDYLVLKPEKGYLVKGNIYPVPDSRFPFLGVHFTPRLDGSIWLGPNAVLAFKREGYRPFDFNARDVMEVILKSGFIKLVFQNFSYGVNEMYKACFLSETVKHLQKFIPEITISDVLRGPAGVRAQALDRDGNLVEDFVFDGGAGEIGDRILHVRNAPSPAATSSLAISRMIAEEVQQRFKL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using MAFFT. Conservation and consensus calculated using von Neumann entropy from PFAAT.