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CDK14 a protein kinase of the CDK family. May play a role in meiosis as well as in neuron differentiation and/or function. Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: CDK family; CDK/TAIRE subfamily; CMGC group; Cell cycle regulation; EC; Kinase, protein; Motility/polarity/chemotaxis; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); TAIRE subfamily
Chromosomal Location of Human Ortholog: 7q21.13
Cellular Component: cytoplasm; cytoplasmic cyclin-dependent protein kinase holoenzyme complex; cytosol; nucleus; plasma membrane
Molecular Function: ATP binding; cyclin binding; cyclin-dependent protein kinase activity; protein binding
Biological Process: cell division; G2/M transition of mitotic cell cycle; protein amino acid phosphorylation; regulation of cell cycle; Wnt signaling pathway
Reference #:  O94921 (UniProtKB)
Alt. Names/Synonyms: CDK14; Cell division protein kinase 14; cyclin-dependent kinase 14; hPFTAIRE1; KIAA0834; PFTAIRE protein kinase 1; PFTAIRE1; PFTK1; Serine/threonine-protein kinase PFTAIRE-1
Gene Symbols: CDK14
Molecular weight: 53,057 Da
Basal Isoelectric point: 9.06  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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