Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Molecular Function: DNA binding; DNA binding transcription factor activity; double-stranded DNA binding
Biological Process: anterior commissure morphogenesis; chondrocyte differentiation; DNA replication; forebrain development; glial cell differentiation; hindbrain development; lung development; negative regulation of cell proliferation; negative regulation of DNA binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; principal sensory nucleus of trigeminal nerve development; regulation of transcription, DNA-templated; transcription, DNA-dependent