Activates erythroid-specific, globin gene expression. Interacts with KEAP1. Belongs to the bZIP family. CNC subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum membrane; integral component of membrane; nucleus; protein complex
Molecular Function: DNA binding transcription factor activity; protein binding; protein complex binding; protein domain specific binding; transcription cofactor activity
Biological Process: anatomical structure morphogenesis; erythrocyte differentiation; heme biosynthetic process; inflammatory response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter