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Protein Page:
UACA

Overview
UACA Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Note: This description may include information from UniProtKB.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 15q23
Cellular Component: cytosol; nucleus
Molecular Function: protein binding
Reference #:  Q9BZF9 (UniProtKB)
Alt. Names/Synonyms: FLJ10128; KIAA1561; MGC141967; MGC141969; nuclear membrane binding protein; NUCLING; UACA; uveal autoantigen with coiled coil domains and ankyrin repeats; Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Symbols: UACA
Molecular weight: 162,505 Da
Basal Isoelectric point: 6.6  Predict pI for various phosphorylation states
Select Structure to View Below

UACA

Protein Structure Not Found.

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