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SSU72 May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination. Belongs to the SSU72 phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC; Phosphatase
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: cytosol; mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm
Molecular Function: CTD phosphatase activity; protein binding
Biological Process: mRNA polyadenylation; termination of RNA polymerase II transcription
Reference #:  Q9NP77 (UniProtKB)
Alt. Names/Synonyms: CTD phosphatase SSU72; FLJ13048; HSPC182; PNAS-120; RNA polymerase II subunit A C-terminal domain phosphatase SSU72; SSU72; Ssu72 RNA polymerase II CTD phosphatase homolog; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
Gene Symbols: SSU72
Molecular weight: 22,574 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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