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Protein Page:

POU4F2 Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 4q31.22
Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus
Molecular Function: transcription coactivator activity; transcription corepressor activity
Biological Process: axon guidance; estrogen receptor signaling pathway; MAPKKK cascade; negative regulation of cell differentiation; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; positive regulation of axon extension; positive regulation of cell differentiation; positive regulation of osteoclast differentiation; positive regulation of programmed cell death; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription factor activity; retina development in camera-type eye
Reference #:  Q12837 (UniProtKB)
Alt. Names/Synonyms: Brain-3B; Brain-specific homeobox/POU domain protein 3B; Brn-3B; BRN3.2; BRN3B; Brn3b POU domain transcription factor; PO4F2; POU class 4 homeobox 2; POU domain class 4 transcription factor 2; POU domain protein; POU domain, class 4, transcription factor 2; POU4F2
Gene Symbols: POU4F2
Molecular weight: 43,087 Da
Basal Isoelectric point: 9.33  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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