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SEC24C Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. Interacts with SLC6A4. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. SEC24C is capable of forming heterodimers with SEC24A. Interacts with TMED2 and TMED10. Ubiquitous. Belongs to the SEC23/SEC24 family. SEC24 subfamily. Note: This description may include information from UniProtKB.
Protein type: Motor
Chromosomal Location of Human Ortholog: 10q22.2
Cellular Component: COPII vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi membrane
Molecular Function: protein binding; SNARE binding; zinc ion binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII vesicle coating; ER to Golgi vesicle-mediated transport; in utero embryonic development; intracellular protein transport
Reference #:  P53992 (UniProtKB)
Alt. Names/Synonyms: KIAA0079; Protein transport protein Sec24C; SC24C; SEC24 family, member C (S. cerevisiae); SEC24 related gene family, member C; SEC24-related protein C; SEC24C
Gene Symbols: SEC24C
Molecular weight: 118,325 Da
Basal Isoelectric point: 6.71  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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