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Protein Page:
BKR2

Overview
BKR2 a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6q32
Cellular Component: endosome; plasma membrane
Molecular Function: beta-2 adrenergic receptor binding; bradykinin receptor activity; protease binding; protein binding; protein heterodimerization activity; type 1 angiotensin receptor binding
Biological Process: acute inflammatory response to antigenic stimulus; arachidonic acid secretion; elevation of cytosolic calcium ion concentration; negative regulation of blood pressure; negative regulation of cell proliferation; negative regulation of peptidyl-serine phosphorylation; response to drug; response to salt stress; sensory perception of pain; vasodilation
Reference #:  P25023 (UniProtKB)
Alt. Names/Synonyms: B2 bradykinin receptor; B2BKR; B2BRA; B2R; Bdkrb2; BK-2 receptor; BKRB2; bradykinin receptor B2; bradykinin receptor, beta 2
Gene Symbols: Bdkrb2
Molecular weight: 44,930 Da
Basal Isoelectric point: 8.79  Predict pI for various phosphorylation states
Select Structure to View Below

BKR2

Protein Structure Not Found.

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