a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Molecular Function: beta-2 adrenergic receptor binding; bradykinin receptor activity; protease binding; protein binding; protein heterodimerization activity; type 1 angiotensin receptor binding
Biological Process: acute inflammatory response to antigenic stimulus; arachidonic acid secretion; elevation of cytosolic calcium ion concentration; negative regulation of blood pressure; negative regulation of cell proliferation; negative regulation of peptidyl-serine phosphorylation; response to drug; response to salt stress; sensory perception of pain; vasodilation