Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:

INDOL1 Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - tryptophan; EC 1.13.11.-; Oxidoreductase
Chromosomal Location of Human Ortholog: 8|8 A2
Cellular Component: cytoplasm
Molecular Function: dioxygenase activity; heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; oxidoreductase activity; tryptophan 2,3-dioxygenase activity
Biological Process: immune system process; tryptophan catabolic process; tryptophan catabolic process to kynurenine
Reference #:  Q8R0V5 (UniProtKB)
Alt. Names/Synonyms: AI265623; C230043N17Rik; I23O2; IDO-2; Ido2; Indol1; Indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase-like protein 1; indoleamine-pyrrole 2,3 dioxygenase-like 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1; MGC31194
Gene Symbols: Ido2
Molecular weight: 45,255 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

STRING  |  Reactome  |  BioGPS  |  Scansite  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene