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Protein Page:

LHX6 Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 9q33.2
Cellular Component: nucleus
Molecular Function: DNA binding transcription factor activity; metal ion binding; protein binding; sequence-specific DNA binding
Biological Process: cell maturation; cerebral cortex GABAergic interneuron migration; cerebral cortex radially oriented cell migration; cerebral cortex tangential migration; regulation of transcription, DNA-templated; transcription, DNA-dependent
Reference #:  Q9UPM6 (UniProtKB)
Alt. Names/Synonyms: LHX6; LHX6.1; LIM homeobox 6; LIM homeobox protein 6; LIM homeodomain protein 6.1; LIM/homeobox protein Lhx6; LIM/homeobox protein Lhx6.1; MGC119542; MGC119544; MGC119545
Gene Symbols: LHX6
Molecular weight: 40,045 Da
Basal Isoelectric point: 8.77  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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