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Ostb Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities. Belongs to the OST-beta family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: integral component of membrane; plasma membrane; protein complex
Molecular Function: protein heterodimerization activity; transporter activity
Biological Process: bile acid and bile salt transport; positive regulation of protein glycosylation; regulation of protein stability
Reference #:  Q86UW2 (UniProtKB)
Alt. Names/Synonyms: FLJ26090; MGC118959; MGC118960; MGC118961; organic solute transporter beta; Organic solute transporter subunit beta; OST-beta; OSTB; OSTBETA
Gene Symbols: SLC51B
Molecular weight: 14,346 Da
Basal Isoelectric point: 4.58  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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