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Protein Page:
eplin

Overview
eplin Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments. 4 isoforms of the human protein are produced by alternative promoter. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12q13.12
Cellular Component: actin cytoskeleton; cleavage furrow; focal adhesion; stress fiber
Molecular Function: actin filament binding; actin monomer binding; cadherin binding; protein binding
Biological Process: actin filament bundle formation; negative regulation of actin filament depolymerization; ruffle organization and biogenesis
Reference #:  Q9UHB6 (UniProtKB)
Alt. Names/Synonyms: 1110021C24Rik; Epithelial protein lost in neoplasm; epithelial protein lost in neoplasm beta; EPLIN; FLJ38853; LIM domain and actin binding 1; LIM domain and actin-binding protein 1; LIMA1; MGC131726; SREBP3; sterol regulatory element binding protein 3
Gene Symbols: LIMA1
Molecular weight: 85,226 Da
Basal Isoelectric point: 6.41  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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eplin

Protein Structure Not Found.
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