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CRYGD a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2q33.3
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: lens development in camera-type eye; visual perception
Disease: Cataract 4, Multiple Types
Reference #:  P07320 (UniProtKB)
Alt. Names/Synonyms: CACA; CCA3; CCP; CRGD; cry-g-D; CRYG4; CRYGD; crystallin, gamma D; gamma crystallin 4; Gamma-crystallin 4; Gamma-crystallin D; Gamma-D-crystallin
Gene Symbols: CRYGD
Molecular weight: 20,738 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
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Protein Structure Not Found.
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