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Protein Page:

GBX2 May act as a transcription factor for cell pluripotency and differentiation in the embryo. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q37.2
Cellular Component: nucleus
Molecular Function: DNA binding transcription factor activity
Biological Process: autonomic nervous system development; axon guidance; branching involved in blood vessel morphogenesis; cerebellum development; forebrain neuron development; granule cell precursor proliferation; inner ear morphogenesis; midbrain-hindbrain boundary morphogenesis; nervous system development; neural crest cell migration; positive regulation of transcription from RNA polymerase II promoter; rhombomere 2 development; thalamus development; transcription from RNA polymerase II promoter
Reference #:  P52951 (UniProtKB)
Alt. Names/Synonyms: Gastrulation and brain-specific homeobox protein 2; gastrulation brain homeo box 2; gastrulation brain homeobox 2; GBX2; Homeobox protein GBX-2
Gene Symbols: GBX2
Molecular weight: 37,348 Da
Basal Isoelectric point: 8.43  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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