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TNNC2 Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: cytosol; troponin complex
Molecular Function: actin binding; actin filament binding; calcium ion binding; calcium-dependent protein binding; protein binding
Biological Process: muscle filament sliding; regulation of muscle contraction; skeletal muscle contraction
Reference #:  P02585 (UniProtKB)
Alt. Names/Synonyms: TNNC2; troponin C type 2 (fast); Troponin C, skeletal muscle; troponin C2, fast
Gene Symbols: TNNC2
Molecular weight: 18,122 Da
Basal Isoelectric point: 4.06  Predict pI for various phosphorylation states
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