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Protein Page:
WNT8B

Overview
WNT8B Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. Belongs to the Wnt family. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q24.31
Cellular Component: extracellular region; extracellular space; proteinaceous extracellular matrix
Molecular Function: frizzled binding; receptor ligand activity
Biological Process: cell fate commitment; determination of dorsal identity; gastrulation; nervous system development; neuron differentiation; response to estradiol; response to retinoic acid; signal transduction; Wnt receptor signaling pathway through beta-catenin; Wnt signaling pathway
Reference #:  Q93098 (UniProtKB)
Alt. Names/Synonyms: Protein Wnt-8b; wingless-type MMTV integration site family, member 8B; WNT8B
Gene Symbols: WNT8B
Molecular weight: 38,721 Da
Basal Isoelectric point: 8.93  Predict pI for various phosphorylation states
CST Pathways:  ESC Pluripotency and Differentiation  |  Microtubule Dynamics  |  mTOR Signaling  |  Translation: eIF4E and p70S6K  |  Wnt/ß-Catenin Signaling
Select Structure to View Below

WNT8B

Protein Structure Not Found.

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