Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
Home | Login
About PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Search / Browse Functions
Protein Page:

EPB41L3 a possible tumor suppressor protein that plays a role in cell adhesion and apoptosis. Critical growth regulator in the pathogenesis of meningiomas. Three alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Tumor suppressor
Chromosomal Location of Human Ortholog: 18p11.31
Cellular Component: axolemma; cytoskeleton; cytosol; intercellular junction; juxtaparanode region of axon; paranode region of axon; plasma membrane; postsynaptic density
Molecular Function: actin binding; protein binding; structural constituent of cytoskeleton
Biological Process: actomyosin structure organization; apoptosis; cortical actin cytoskeleton organization and biogenesis; cortical cytoskeleton organization; cytoskeletal anchoring; myelin maintenance; neuron projection morphogenesis; paranodal junction assembly; protein localization to plasma membrane; regulation of cell growth; regulation of cell shape
Reference #:  Q9Y2J2 (UniProtKB)
Alt. Names/Synonyms: 4.1B; Band 4.1-like protein 3; DAL-1; DAL1; Differentially expressed in adenocarcinoma of the lung protein 1; E41L3; EPB41L3; erythrocyte membrane protein band 4.1-like 3; FLJ37633; KIAA0987
Gene Symbols: EPB41L3
Molecular weight: 120,678 Da
Basal Isoelectric point: 5.09  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB