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SLC5A3 a sodium/myo-inositol cotransporter. An integral membrane protein. Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function. Belongs to the sodium:solute symporter (SSF) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 21q22.11
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: myo-inositol:sodium symporter activity; symporter activity
Biological Process: inositol metabolic process; myo-inositol transport; transport
Reference #:  P53794 (UniProtKB)
Alt. Names/Synonyms: human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; SC5A3; SLC5A3; SMIT; SMIT2; Sodium/myo-inositol cotransporter; sodium/myo-inositol cotransporter 1; solute carrier family 5 (inositol transporter), member 3; solute carrier family 5 (inositol transporters), member 3; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Solute carrier family 5 member 3
Gene Symbols: SLC5A3
Molecular weight: 79,694 Da
Basal Isoelectric point: 7.01  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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