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TUBA4A Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: cytosol; extracellular region; microtubule; microtubule cytoskeleton
Molecular Function: protein binding
Biological Process: G2/M transition of mitotic cell cycle; platelet degranulation
Disease: Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia
Reference #:  P68366 (UniProtKB)
Alt. Names/Synonyms: Alpha-tubulin 1; FLJ30169; H2-ALPHA; TBA4A; Testis-specific alpha-tubulin; TUBA1; TUBA4A; Tubulin alpha-1 chain; Tubulin alpha-4A chain; Tubulin H2-alpha; tubulin, alpha 1 (testis specific); tubulin, alpha 4a
Gene Symbols: TUBA4A
Molecular weight: 49,924 Da
Basal Isoelectric point: 4.95  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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