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Protein Page:
RGS11

Overview
RGS11 Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: cytoplasm; heterotrimeric G-protein complex; plasma membrane; protein complex
Molecular Function: G-protein beta-subunit binding; GTPase activator activity; signal transducer activity
Biological Process: G-protein coupled receptor signaling pathway; negative regulation of signal transduction; positive regulation of GTPase activity; regulation of G-protein coupled receptor protein signaling pathway
Reference #:  O94810 (UniProtKB)
Alt. Names/Synonyms: Regulator of G-protein signaling 11; regulator of G-protein signalling 11; RGS11; RS11
Gene Symbols: RGS11
Molecular weight: 52,946 Da
Basal Isoelectric point: 8.99  Predict pI for various phosphorylation states
CST Pathways:  GPCR Signaling to MAPKs
Select Structure to View Below

RGS11

Protein Structure Not Found.

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